Evidence map›Paper›PMID 22274744›Full record

ArticlePlant signaling & behavior2012

Reduced levels of class 1 reversibly glycosylated polypeptide increase intercellular transport via plasmodesmata.

Tessa M Burch-Smith, Ya Cui, Patricia C Zambryski

Open access · bronzeAbstract read
In one paragraph

Article in Plant signaling & behavior, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Cellular Partners of Tobamoviral Movement Proteins.International journal of molecular sciences · 2025
    Review
  3. International journal of molecular sciences · 2023
    Article
  4. Transcriptome Analysis of Air Space-Type Variegation Formation inInternational journal of molecular sciences · 2022
    Article
  5. Review
  6. Review
  7. Review
  8. Gene Expression, Protein Function and Pathways ofNanomaterials (Basel, Switzerland) · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tessa M Burch-SmithDepartment of Plant and Microbial Biology, Koshland Hall, University of California, Berkeley, CA, USA.
Ya Cui
Patricia C Zambryski
University of California System · USBerkeley College · US

Funding

VIRAL AND DEVELOPMENTAL REGULATION OF PLASMODESMATAR01GM045244 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI ZAMBRYSKI, PATRICIA C. · 1991 to 2012
$2.6M
"Analyses of two genes that affect plasmodesmata structure and function"R56GM045244 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI ZAMBRYSKI, PATRICIA C. · 2007 to 2007
$279k
NIGMS NIH HHS GM45244NIGMS NIH HHS R01 GM045244NIGMS NIH HHS R56 GM045244
6 · The paper itself

Abstract

Maize and Arabidopsis thaliana class 1 reversibly glycosylated polypeptides (C1RGPs) are plasmodesmata-associated proteins. Previously, over-expression of Arabidopsis C1RGP AtRGP2 in Nicotiana tabacum was shown to reduce intercellular transport of photoassimilate, resulting in stunted, chlorotic plants, and inhibition of local cell-to-cell spread of tobacco mosaic virus (TMV). Here, we used virus induced gene silencing to examine the effects of reduced levels of C1RGPs in Nicotiana benthamiana. Silenced plants show wild-type growth and development. Intercellular transport in silenced plants was probed using fluorescently labeled TMV and its movement protein, P30. P30 shows increased cell-to-cell movement and TMV exhibited accelerated systemic spread compared to control plants. These results support the hypothesis that C1RGPs act to regulate intercellular transport via plasmodesmata.

Indexed as

ArabidopsisArabidopsis ProteinsGene SilencingGlycosylationNicotianaPlasmodesmataProtein TransportTobacco Mosaic VirusArabidopsis Proteins

Identifiers

PMID22274744
PMCPMC3357371
OpenAlexW2132538709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.