ReviewCell adhesion & migration
Can mesenchymal cells undergo collective cell migration? The case of the neural crest.
Review in Cell adhesion & migration. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- Migrating mesoderm cells self-organize into a dynamic meshwork structure during chick gastrulation.eLife · 2025Article
- Plexin/Semaphorin antagonism orchestrates collective cell migration and organ sculpting by regulating epithelial-mesenchymal balance.Science advances · 2025Article
- Schwann cells in regeneration and cancer: an epithelial-mesenchymal transition perspective.Open biology · 2025Review
- Androgen-regulatediScience · 2022Article
- In toto imaging of early enteric nervous system development reveals that gut colonization is tied to proliferation downstream of Ret.Development (Cambridge, England) · 2022Article
- Viscoelasticity, Like Forces, Plays a Role in Mechanotransduction.Frontiers in cell and developmental biology · 2022Review
- The plasticity of pancreatic cancer stem cells: implications in therapeutic resistance.Cancer metastasis reviews · 2021Review
- Review
- Rules of collective migration: from the wildebeest to the neural crest.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- The extracellular matrix in development.Development (Cambridge, England) · 2020Review
- FNDC3B circular RNA promotes the migration and invasion of gastric cancer cells via the regulation of E-cadherin and CD44 expression.Journal of cellular physiology · 2019Article
- Microtubules: Evolving roles and critical cellular interactions.Experimental biology and medicine (Maywood, N.J.) · 2019Review
- Integrating chemical and mechanical signals in neural crest cell migration.Current opinion in genetics & development · 2019Review
- N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis.Developmental biology · 2017Article
- Tuning Collective Cell Migration by Cell-Cell Junction Regulation.Cold Spring Harbor perspectives in biology · 2017Review
- Rac GTPase regulation of 3D invasion in neuroblastomas lacking MYCN amplification.Cell adhesion & migration · 2017Article
- Modelling collective cell migration of neural crest.Current opinion in cell biology · 2016Review
- Control of the collective migration of enteric neural crest cells by the Complement anaphylatoxin C3a and N-cadherin.Developmental biology · 2016Article
- Cadherin-11 localizes to focal adhesions and promotes cell-substrate adhesion.Nature communications · 2016Article
- SPECC1L deficiency results in increased adherens junction stability and reduced cranial neural crest cell delamination.Scientific reports · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Cell migration is critical for proper development of the embryo and is also used by many cell types to perform their physiological function. For instance, cell migration is essential for immune cells to monitor the body and for epithelial cells to heal a wound whereas, in cancer cells, acquisition of migratory capabilities is a critical step towards malignancy. Migratory cells are often categorized into two groups: mesenchymal cells, produced by an epithelium-to-mesenchyme transition, that undergo solitary migration and epithelial-like cells which migrate collectively. However, on some occasions, mesenchymal cells may travel in large, dense groups and exhibit key features of collectively migrating cells such as coordination and cooperation. Here, using data published on Neural Crest cells, a highly invasive mesenchymal cell population that extensively migrate throughout the embryo, we explore the idea that other mesenchymal cells, including cancer cells, might be able to undergo collective cell migration under certain conditions and discuss how they could do so.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.