ReviewCurrent opinion in cardiology2012
Advances in pediatric pulmonary arterial hypertension.
Review in Current opinion in cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Pediatric Cardiac Intensive Care Society 2014 Consensus Statement: Pharmacotherapies in Cardiac Critical Care Pulmonary Hypertension.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2016Guideline
- Right ventricular-vascular coupling ratio in pediatric pulmonary arterial hypertension: A comparison between cardiac magnetic resonance and right heart catheterization measurements.International journal of cardiology · 2019Article
- The Role of Biomarkers and Surrogate End Points in Drug Development for Neonatal Pulmonary Arterial Hypertension.NeoReviews · 2016Article
- Article
- Trends in pediatric pulmonary hypertension-related hospitalizations in the United States from 2000-2009.Pulmonary circulation · 2015Article
- Serum Pentraxin 3 and hs-CRP Levels in Children with Severe Pulmonary Hypertension.Balkan medical journal · 2014Article
- Perioperative pharmacological management of pulmonary hypertensive crisis during congenital heart surgery.Pulmonary circulation · 2014Review
- Biomarkers for pediatric pulmonary arterial hypertension - a call to collaborate.Frontiers in pediatrics · 2014Review
- Prenatal programming of pulmonary hypertension induced by chronic hypoxia or ductal ligation in sheep.Pulmonary circulation · 2013Review
- A 6 year-old boy was referred from a district hospital with congestive cardiac failure.Malawi medical journal : the journal of Medical Association of Malawi · 2013Article
- Acute pulmonary vasodilator testing with inhaled treprostinil in children with pulmonary arterial hypertension.Pediatric cardiology · 2013Article
- Epidemiology and clinical management of pulmonary hypertension in children.Korean circulation journal · 2012Article
- Circulating cytokines and growth factors in pediatric pulmonary hypertension.Mediators of inflammation · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
purpose of reviewPulmonary arterial hypertension (PAH) is an important cause of morbidity and mortality in children. Approved medications for the treatment of adult PAH have been used to treat children, but evidence-based treatment algorithms for children are lacking. RECENT
findingsPediatric PAH registries have begun to define the incidence and prevalence of idiopathic PAH and PAH associated with congenital heart disease. A pediatric-specific classification of pulmonary hypertensive vascular disease has been proposed. Furthermore, the first randomized placebo-controlled trial of type-5 phosphodiesterase therapy in treatment-naïve children with PAH has been completed and reported. This trial highlights the importance of the difficulties of performing clinical trials in children with targeted PAH therapy as well as the importance of long-term follow-up of adverse events. SUMMARY: Classification, clinical trials, and therapy for children with PAH must take into account the unique aspects of PAH in children.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.