ArticleOptics express2012
Quantitative sectioning and noise analysis for structured illumination microscopy.
Article in Optics express, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Structured illumination microscopy for high SNR 3D imaging from millimeter-thick tissues to cellular dynamics.Innovation (Cambridge (Mass.)) · 2026Article
- Quantifying optical sectioning in reflection microscopy with patterned illumination.Biomedical optics express · 2026Article
- Optical sectioning methods in three-dimensional bioimaging.Light, science & applications · 2025Review
- High-speed in vivo calcium recording using structured illumination with self-supervised denoising.Optics continuum · 2024Article
- Rapid slide-free and non-destructive histological imaging using wide-field optical-sectioning microscopy.Biomedical optics express · 2022Article
- MANF supports the inner hair cell synapse and the outer hair cell stereocilia bundle in the cochlea.Life science alliance · 2022Article
- Background inhibited and speed-loss-free volumetric imagingFrontiers in neuroscience · 2022Article
- Review of bio-optical imaging systems with a high space-bandwidth product.Advanced photonics · 2021Article
- Single-scan HiLo with line-illumination strategy for optical section imaging of thick tissues.Biomedical optics express · 2021Article
- New 1,3-Disubstituted Benzo[Molecules (Basel, Switzerland) · 2020Article
- Fast widefield imaging of neuronal structure and function with optical sectioning in vivo.Science advances · 2020Article
- Automatic motion compensation for structured illumination endomicroscopy using a flexible fiber bundle.Journal of biomedical optics · 2020Article
- Improved contrast in inverted selective plane illumination microscopy of thick tissues using confocal detection and structured illumination.Biomedical optics express · 2017Article
- Optically sectioned wide-field fluorescence lifetime imaging microscopy enabled by structured illumination.Biomedical optics express · 2017Article
- Rapid staining and imaging of subnuclear features to differentiate between malignant and benign breast tissues at a point-of-care setting.Journal of cancer research and clinical oncology · 2016Article
- Gigapixel surface imaging of radical prostatectomy specimens for comprehensive detection of cancer-positive surgical margins using structured illumination microscopy.Scientific reports · 2016Article
- Evaluating the performance of time-gated live-cell microscopy with lanthanide probes.Biophysical journal · 2015Article
- Any Way You Slice It-A Comparison of Confocal Microscopy Techniques.Journal of biomolecular techniques : JBT · 2015Article
- QSIM: quantitative structured illumination microscopy image processing in ImageJ.Biomedical engineering online · 2015Article
- Optically-sectioned two-shot structured illumination microscopy with Hilbert-Huang processing.Optics express · 2014Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
Abstract
Structured illumination (SI) has long been regarded as a nonquantitative technique for obtaining sectioned microscopic images. Its lack of quantitative results has restricted the use of SI sectioning to qualitative imaging experiments, and has also limited researchers' ability to compare SI against competing sectioning methods such as confocal microscopy. We show how to modify the standard SI sectioning algorithm to make the technique quantitative, and provide formulas for calculating the noise in the sectioned images. The results indicate that, for an illumination source providing the same spatially-integrated photon flux at the object plane, and for the same effective slice thicknesses, SI sectioning can provide higher SNR images than confocal microscopy for an equivalent setup when the modulation contrast exceeds about 0.09.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.