ArticleOptics express2011
A forward-imaging needle-type OCT probe for image guided stereotactic procedures.
Article in Optics express, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 79 citations in OpenAlex.
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- Computer-aided Veress needle guidance using endoscopic optical coherence tomography and convolutional neural networks.Journal of biophotonics · 2022Article
- Development of Guidance Techniques for Regional Anesthesia: Past, Present and Future.Journal of pain research · 2021Review
- Theranostic OCT microneedle for fast ultrahigh-resolution deep-brain imaging and efficient laser ablation in vivo.Science advances · 2020Article
- Towards an Optical Biopsy during Visceral Surgical Interventions.Visceral medicine · 2020Review
- Full-field swept-source optical coherence tomography and neural tissue classification for deep brain imaging.Journal of biophotonics · 2020Article
- Quantitative nontumorous and tumorous human brain tissue assessment using microstructural co- and cross-polarized optical coherence tomography.Scientific reports · 2019Article
- Cross-Polarization Optical Coherence Tomography for Brain Tumor Imaging.Frontiers in oncology · 2019Article
- Intraoperative detection of blood vessels with an imaging needle during neurosurgery in humans.Science advances · 2018Article
- Needle-based Optical Coherence Tomography to Guide Transbronchial Lymph Node Biopsy.Journal of bronchology & interventional pulmonology · 2018Article
- Clinical translation of handheld optical coherence tomography: practical considerations and recent advancements.Journal of biomedical optics · 2017Article
- Endoscopic optical coherence tomography: technologies and clinical applications [Invited].Biomedical optics express · 2017Article
- High-dynamic-range fluorescence laminar optical tomography (HDR-FLOT).Biomedical optics express · 2017Article
- Review of intraoperative optical coherence tomography: technology and applications [Invited].Biomedical optics express · 2017Article
- Depth-resolved imaging of colon tumor using optical coherence tomography and fluorescence laminar optical tomography.Biomedical optics express · 2016Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
A forward-imaging needle-type optical coherence tomography (OCT) probe with Doppler OCT (DOCT) capability has the potential to solve critical challenges in interventional procedures. A case in point is stereotactic neurosurgery where probes are advanced into the brain based on predetermined coordinates. Laceration of blood vessels in front of the advancing probe is an unavoidable complication with current methods. Moreover, cerebrospinal fluid (CSF) leakage during surgery can shift the brain rendering the predetermined coordinates unreliable. In order to address these challenges, we developed a forward-imaging OCT probe (740 μm O.D.) using a gradient-index (GRIN) rod lens that can provide real-time imaging feedback for avoiding at-risk vessels (8 frames/s with 1024 A-scans per frame for OCT/DOCT dual imaging) and guiding the instrument to specific targets with 12 μm axial resolution (100 frames/s with 160 A-scans per frame for OCT imaging only). The high signal-to-background characteristic of DOCT provides exceptional sensitivity in detecting and quantifying the blood flow within the sheep brain parenchyma in real time. The OCT/DOCT dual imaging also demonstrated its capability to differentiate the vessel type (artery/vein) on rat's femoral vessels. We also demonstrated in ex vivo human brain that the location of the tip of the OCT probe can be inferred from micro-anatomical landmarks in OCT images. These findings demonstrate the suitability of OCT guidance during stereotactic procedures in the brain and its potential for reducing the risk of cerebral hemorrhage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.