ArticleInternational journal of molecular sciences2011
Inference of gene regulation via miRNAs during ES cell differentiation using MiRaGE method.
Article in International journal of molecular sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Glutamatergic Neurons Differentiated from Embryonic Stem Cells: An Investigation of Differentiation and Associated Diseases.International journal of molecular sciences · 2021Review
- Clinical significance of miRNA - 106a in non-small cell lung cancer patients who received cisplatin combined with gemcitabine chemotherapy.Cancer biology & medicine · 2018Article
- Apparent microRNA-Target-specific Histone Modification in Mammalian Spermatogenesis.Evolutionary bioinformatics online · 2015Article
- Towards Clinical Applications of Blood-Borne miRNA Signatures: The Influence of the Anticoagulant EDTA on miRNA Abundance.PloS one · 2015Article
- miRNAs can be generally associated with human pathologies as exemplified for miR-144.BMC medicine · 2014Article
- The human miRNA repertoire of different blood compounds.BMC genomics · 2014Article
- Inference of Target Gene Regulation via miRNAs during Cell Senescence by Using the MiRaGE Server.Aging and disease · 2012Article
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3 authors.
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Abstract
MicroRNA (miRNA) is a critical regulator of cell growth, differentiation, and development. To identify important miRNAs in a biological process, many bioinformatical tools have been developed. We have developed MiRaGE (MiRNA Ranking by Gene Expression) method to infer the regulation of gene expression by miRNAs from changes of gene expression profiles. The method does not require precedent array normalization. We applied the method to elucidate possibly important miRNAs during embryonic stem (ES) cell differentiation to neuronal cells and we infer that certain miRNAs, including miR-200 family, miR-429, miR-302 family, and miR-17-92 cluster members may be important to the maintenance of undifferentiated status in ES cells.
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