ReviewInternational journal of molecular sciences2011
Mechanobiology of platelets: techniques to study the role of fluid flow and platelet retraction forces at the micro- and nano-scale.
Review in International journal of molecular sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Mechanotransduction of Magnetically Applied Forces Leads to Mechanical Stiffening of Platelet-Rich Plugs.Advanced healthcare materials · 2026Article
- Diagnosis of Inherited Platelet Disorders: Clinical Evaluation and Functional and Molecular Assays.Biomolecules · 2025Review
- Distinct platelet F-actin patterns and traction forces on von Willebrand factor versus fibrinogen.Biophysical journal · 2023Article
- Research progress and clinical evaluation of histotripsy: a narrative review.Annals of translational medicine · 2023Review
- Clot Retraction: Cellular Mechanisms and Inhibitors, Measuring Methods, and Clinical Implications.Biomedicines · 2021Review
- Cleavage by MMP-13 renders VWF unable to bind to collagen but increases its platelet reactivity.Journal of thrombosis and haemostasis : JTH · 2020Article
- Missing regions within the molecular architecture of human fibrin clots structurally resolved by XL-MS and integrative structural modeling.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- EWVDV-Mediated Platelet-Targeting Nanoparticles for the Multimodal Imaging of Thrombi at Different Blood Flow Velocities.International journal of nanomedicine · 2020Article
- Contractile forces in platelet aggregates under microfluidic shear gradients reflect platelet inhibition and bleeding risk.Nature communications · 2019Observational
- Integrated Histotripsy and Bubble Coalescence Transducer for Thrombolysis.Ultrasound in medicine & biology · 2018Article
- Nonmuscle Myosin IIA Regulates Platelet Contractile Forces Through Rho Kinase and Myosin Light-Chain Kinase.Journal of biomechanical engineering · 2016Article
- Histotripsy Thrombolysis on Retracted Clots.Ultrasound in medicine & biology · 2016Article
- Rupture Forces among Human Blood Platelets at different Degrees of Activation.Scientific reports · 2016Article
- Effects of different shear rates on the attachment and detachment of platelet thrombi.Molecular medicine reports · 2016Article
- State of the art in platelet function testing.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2013Article
- Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Coagulation involves a complex set of events that are important in maintaining hemostasis. Biochemical interactions are classically known to regulate the hemostatic process, but recent evidence has revealed that mechanical interactions between platelets and their surroundings can also play a substantial role. Investigations into platelet mechanobiology have been challenging however, due to the small dimensions of platelets and their glycoprotein receptors. Platelet researchers have recently turned to microfabricated devices to control these physical, nanometer-scale interactions with a higher degree of precision. These approaches have enabled exciting, new insights into the molecular and biomechanical factors that affect platelets in clot formation. In this review, we highlight the new tools used to understand platelet mechanobiology and the roles of adhesion, shear flow, and retraction forces in clot formation.
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Registered trials
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