Evidence map›Paper›PMID 22271429›Full record

ArticleInternational journal of geriatric psychiatry2012

Association of attentional shift and reversal learning to functional deficits in geriatric depression.

Guy G Potter, Douglas R McQuoid, Martha E Payne, Warren D Taylor, David C Steffens

Abstract read
In one paragraph

Article in International journal of geriatric psychiatry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Dissociable effects of acute SSRI (escitalopram) on executive, learning and emotional functions in healthy humans.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018
    Article
  5. Article
  6. Article
  7. Article
  8. Anxiety and attention shifting in professional baseball players.International journal of sports medicine · 2014
    Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Guy G PotterDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA. guy.potter@duke.edu
Douglas R McQuoid
Martha E Payne
Warren D Taylor
David C Steffens

Funding

Recruitment and Assessment Core Patient RecruitmentP50MH060451 · NIMH · DUKE UNIVERSITY · PI STEFFENS, DAVID C. · 2001 to 2010
$22.3M
Geriatric Depression: Risk Factors for Adverse OutcomesR01MH054846 · NIMH · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI STEFFENS, DAVID C. · 1995 to 2016
$10.1M
Midcareer Investigator Award in Geriatric DepressionK24MH070027 · NIMH · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI STEFFENS, DAVID C. · 2004 to 2013
$1.6M
Anhedonia, Aging, and the Neural Correlates of Attentional Control in DepressionK23MH087741 · NIMH · DUKE UNIVERSITY · PI POTTER, GUY GLENN · 2010 to 2014
$680k
NIMH NIH HHS K23 MH087741NIMH NIH HHS K23MH087741NIMH NIH HHS K24 MH070027NIMH NIH HHS K24MH070027NIMH NIH HHS P50 MH060451NIMH NIH HHS P50MH060451NIMH NIH HHS R01 MH054846NIMH NIH HHS R01MH054846
6 · The paper itself

Abstract

objectiveThe objective of this study is to examine the association between self-reported functional disability in depressed older adults and two types of executive function processes, attentional set shifting and reversal learning.

methodsParticipants (N = 89) were aged 60 or over and enrolled in a naturalistic treatment study of major depressive disorder. Participants provided information on self-reported function in instrumental activities of daily living (IADL) and completed the Intra-Extra Dimensional Set Shift test (IED) from the Cambridge Neuropsychological Testing Automated Battery, which assesses intra-dimensional attentional shifts, extra-dimensional attentional shifts, and reversal learning. Participants were categorized by the presence or absence of IADL difficulties and compared on IED performance using bivariable and multivariable tests.

resultsParticipants who reported IADL difficulties had more errors in extra-dimensional attentional shifting and reversal learning, but intra-dimensional shift errors were not associated with IADLs. Only extra-dimensional shift errors were significant in multivariable models that controlled for age, sex, and depression severity.

conclusionsAttentional shifting across categories (i.e., extra-dimensional) was most strongly associated with increased IADL difficulties among depressed older adults, which make interventions to improve flexible problem solving a potential target for reducing instrumental disability in this population.

Indexed as

Activities of Daily LivingAgedAttentionFemaleGeriatric AssessmentHumansMajor Depressive DisorderMaleNeuropsychological TestsReversal Learning

Identifiers

PMID22271429
PMCPMC3866797

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.