ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2012
Mast cells in the human dura: effects of age and dural bleeding.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 21 citations in OpenAlex.
- Histomorphometry of mast cells in the convexity of human intracranial dura mater.Journal of anatomy · 2022Article
- Meningeal Mast Cells as Key Effectors of Stroke Pathology.Frontiers in cellular neuroscience · 2019Article
- Shared Fate of Meningeal Mast Cells and Sensory Neurons in Migraine.Frontiers in cellular neuroscience · 2019Article
- Mast Cell-Mediated Mechanisms of Nociception.International journal of molecular sciences · 2015Review
- Evidence that meningeal mast cells can worsen stroke pathology in mice.The American journal of pathology · 2014Article
- Mast cells in the human dura: effects of age and dural bleeding.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2013Article
- The pathophysiology of brain swelling associated with subdural hemorrhage: the role of the trigeminovascular system.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2012Review
- Developmental changes in human dural innervation.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2012Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnimal studies have shown that the dura mater contains mast cells. We investigated the density of mast cells in the human dura mater, and the changes associated with subdural haemorrhage (SDH).
methodsSamples of the human dura were stained with tryptase antibody and were examined for mast cells. We used control cases with no dural bleeding (n = 9) and cases of fresh (n = 24) and old (n = 18) dural haemorrhage.
resultsMast cells were easily found in dural samples. The mean density in controls (11.05 cells per mm(2)) was less than that in fresh SDH (15.69), which was less than that in old SDH (23.09).
conclusionsSubdural haemorrhage is associated with an increase in dural mast cell density, and the density increases as the haematoma ages. We hypothesise that dural mast cells may contribute to neurogenic inflammation and the clinical features of subdural haemorrhage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.