Trial reportEuropean journal of applied physiology2012
Characterizing the profile of muscle deoxygenation during ramp incremental exercise in young men.
Trial report in European journal of applied physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed.
- Muscle O2 extraction reserve during intense cycling is site-specific.Journal of applied physiology (Bethesda, Md. : 1985) · 2014Trial
- Running Constraints Shape Multifractal Movement Complexity Beyond Physiological and Mechanical Load: A Pilot Study.Sensors (Basel, Switzerland) · 2026Article
- Visually identified breakpoints in muscle oxygen saturation are not equivalent to ventilatory thresholds in national-level triathletes.European journal of applied physiology · 2026Article
- Assessing the feasibility of near-infrared spectroscopy for evaluating physiological exercise thresholds.Scientific reports · 2025Article
- Physiological Predictors of Peak Velocity in the VAM-EVAL Incremental Test and the Role of Kinematic Variables in Running Economy in Triathletes.Sports (Basel, Switzerland) · 2025Article
- Effects of Compression Garments on Muscle Oxygen Saturation Recovery in the Upper Limbs Using Near-Infrared Spectroscopy.Journal of functional morphology and kinesiology · 2025Article
- Combined effect of sprint interval training and post-exercise blood flow restriction on muscle deoxygenation responses during ramp incremental cycling.European journal of applied physiology · 2025Article
- Assessing Aerobic and Anaerobic Thresholds with Emphasis on Isocapnic Buffering in Endurance Runners.International journal of exercise science · 2025Article
- Comparison of NIRS exercise intensity thresholds with maximal lactate steady state, critical power and rowing performance.Biology of sport · 2024Article
- Muscle deoxygenation during ramp incremental cycle exercise in older adults with type 2 diabetes.European journal of applied physiology · 2024Article
- The effects of endurance training on muscle oxygen desaturation during incremental exercise tests: a systematic review and meta-analysis.Frontiers in sports and active living · 2024Article
- Muscle oxygen saturation rates coincide with lactate-based exercise thresholds.European journal of applied physiology · 2023Article
- AltitudeOmics: effects of 16 days acclimatization to hypobaric hypoxia on muscle oxygen extraction during incremental exercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- Training zones through muscle oxygen saturation during a graded exercise test in cyclists and triathletes.Biology of sport · 2023Article
- Comparing the reliability of muscle oxygen saturation with common performance and physiological markers across cycling exercise intensity.Frontiers in sports and active living · 2023Article
- Differential impact of heat and hypoxia on dynamic oxygen uptake and deoxyhemoglobin parameters during incremental exhaustive exercise.Frontiers in physiology · 2023Article
- The role of the microcirculation and integrative cardiovascular physiology in the pathogenesis of ICU-acquired weakness.Frontiers in physiology · 2023Review
- The effect of severe intensity bouts on muscle oxygen saturation responses in trained cyclists.Frontiers in sports and active living · 2023Article
- Muscle Oxygen Saturation Breakpoints Reflect Ventilatory Thresholds in Both Cycling and Running.Journal of human kinetics · 2022Article
- A longitudinal study on the interchangeable use of whole-body and local exercise thresholds in cycling.European journal of applied physiology · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study characterized the profile of near-infrared spectroscopy (NIRS)-derived muscle deoxygenation (Δ[HHb]) and the tissue oxygenation index (TOI) as a function of absolute (PO(ABS)) and normalized power output (%PO) or oxygen consumption (%VO(2)) during incremental cycling exercise. Eight men (24 ± 5 year) each performed two fatigue-limited ramp incremental cycling tests (20 W min(-1)), during which pulmonary VO(2), Δ[HHb] and TOI were measured continuously. Responses from the two tests were averaged and the TOI (%) and normalized Δ[HHb] (%Δ[HHb]) were plotted against %VO(2), %PO and PO(ABS). The overall responses were modelled using a sigmoid regression (y = f ( 0 ) + A/(1 + e(-(-c+dx)))) and piecewise 'double-linear' function of the predominant adjustment of %Δ[HHb] or TOI observed throughout the middle portion of exercise and the 'plateau' that followed. In ~85% of cases, the corrected Akaike Information Criterion (AIC(C)) was smaller (suggesting one model favoured) for the 'double-linear' compared with the sigmoid regression for both %Δ[HHb] and TOI. Furthermore, the f ( 0 ) and A estimates from the sigmoid regressions of %Δ[HHb] yielded unrealistically large projected peak (f ( 0 ) + A) values (%VO(2p) 114.3 ± 17.5; %PO 113.3 ± 9.5; PO(ABS) 113.5 ± 9.8), suggesting that the sigmoid model does not accurately describe the underlying physiological responses in all subjects and thus may not be appropriate for comparative purposes. Alternatively, the present study proposes that the profile of %Δ[HHb] and TOI during ramp incremental exercise may be more accurately described as consisting of three distinct phases in which there is little adjustment early in the ramp, the predominant increase in %Δ[HHb] (decrease in TOI) is approximately linear and an approximately linear 'plateau' follows.
Indexed as
Identifiers
22270488What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.