Evidence map›Paper›PMID 22270070›Full record

ReviewAllergology international : official journal of the Japanese Society of Allergology2012

TSLP and immune homeostasis.

Shino Hanabuchi, Norihiko Watanabe, Yong-Jun Liu

Open access · goldAbstract readReview
In one paragraph

Review in Allergology international : official journal of the Japanese Society of Allergology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Shino HanabuchiDepartment of Immunology, Center for Cancer Immunology Research, The University of Texas MD Anderson Cancer Center, TX 77004, USA. shanabuc@mdanderson.org
Norihiko Watanabe
Yong-Jun Liu
The University of Texas MD Anderson Cancer Center · USKyoto University · JP

Funding

TSLP and Allergic InflammationR01AI061645 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LIU, YONG-JUN · 2004 to 2008
$1.8M
DC-mediated Homeostatic Prolif. of CD4 T Cells by TSLPR01AI062888 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LIU, YONG-JUN · 2005 to 2009
$1.6M
NIAID NIH HHS R01 AI061645NIAID NIH HHS R01 AI062888
6 · The paper itself

Abstract

In an immune system, dendritic cells (DCs) are professional antigen-presenting cells (APCs) as well as powerful sensors of danger signals. When DCs receive signals from infection and tissue stress, they immediately activate and instruct the initiation of appropriate immune responses to T cells. However, it has remained unclear how the tissue microenvironment in a steady state shapes the function of DCs. Recent many works on thymic stromal lymphopoietin (TSLP), an epithelial cell-derived cytokine that has the strong ability to activate DCs, provide evidence that TSLP mediates crosstalk between epithelial cells and DCs, involving in DC-mediated immune homeostasis. Here, we review recent progress made on how TSLP expressed within the thymus and peripheral lymphoid and non-lymphoid tissues regulates DC-mediated T-cell development in the thymus and T-cell homeostasis in the periphery.

Indexed as

AnimalsCD4-Positive T-LymphocytesCytokinesHomeostasisHumansThymic Stromal LymphopoietinThymus GlandT-Lymphocytes, RegulatoryCytokinesThymic Stromal Lymphopoietin

Identifiers

PMID22270070
PMCPMC3652583
OpenAlexW2025116855

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.