ArticleThe Journal of clinical investigation2012
Yes, even human brown fat is on fire!
Article in The Journal of clinical investigation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 68 citations in OpenAlex.
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- Adipokines as Cardioprotective Factors: BAT Steps Up to the Plate.Biomedicines · 2025Review
- A century of exercise physiology: concepts that ignited the study of human thermoregulation. Part 3: Heat and cold tolerance during exercise.European journal of applied physiology · 2024Review
- Absolute thermometry of human brown adipose tissue by magnetic resonance with laser polarizedCommunications medicine · 2023Article
- Determination of the Effects of a Series of Ten Whole-Body Cryostimulation Sessions on Physiological Responses to Exercise and Skin Temperature Behavior following Exercise in Elite Athletes.Journal of clinical medicine · 2023Article
- Neuro-Vulnerability in Energy Metabolism Regulation: A Comprehensive Narrative Review.Nutrients · 2023Review
- In vivo imaging of brown adipose tissue vasculature reactivity during adrenergic stimulation of non-shivering thermogenesis in mice.Scientific reports · 2022Article
- No association of BMI and body adiposity with cardiometabolic biomarkers among a small sample of reindeer herders of sub-Arctic Finland.International journal of circumpolar health · 2022Article
- Brown adipose tissue thermogenesis among a small sample of reindeer herders from sub-Arctic Finland.Journal of physiological anthropology · 2022Article
- It Is Not Just Fat: Dissecting the Heterogeneity of Adipose Tissue Function.Current diabetes reports · 2022Review
- Brown Adipose Tissue and Novel Management Strategies for Polycystic Ovary Syndrome Therapy.Frontiers in endocrinology · 2022Review
- The Effect of Repetitive Whole Body Cryotherapy Treatment on Adaptations to a Strength and Endurance Training Programme in Physically Active Males.Frontiers in sports and active living · 2022Article
- Adaptive thermogenesis in brown adipose tissue involves activation of pannexin-1 channels.Molecular metabolism · 2021Article
- Dopamine receptor D1- and D2-agonists do not spark brown adipose tissue thermogenesis in mice.Scientific reports · 2020Article
- Control of Adipose Cell Browning and Its Therapeutic Potential.Metabolites · 2020Review
- Role of Cannabinoids in Obesity.International journal of molecular sciences · 2018Review
- Recent advances in our understanding of brown and beige adipose tissue: the good fat that keeps you healthy.F1000Research · 2018Review
- Effect of Iodothyronines on Thermogenesis: Focus on Brown Adipose Tissue.Frontiers in endocrinology · 2018Review
- Contributors to Metabolic Disease Risk Following Spinal Cord Injury.Current physical medicine and rehabilitation reports · 2016Article
- Effects of pterostilbene in brown adipose tissue from obese rats.Journal of physiology and biochemistry · 2016Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
That adult humans possess brown fat is now accepted - but is the brown fat metabolically active? Does human brown fat actually combust fat to release heat? In this issue of the JCI, Ouellet et al. demonstrate that metabolism in brown fat really is increased when adult humans are exposed to cold. This boosts the possibility that calorie combustion in brown fat may be of significance for our metabolism and, correspondingly, that the absence of brown fat may increase our proneness to obesity - provided that brown fat becomes activated not only by cold but also through food-related stimuli.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.