ArticleJournal of mathematical neuroscience2011
The dynamics underlying pseudo-plateau bursting in a pituitary cell model.
Article in Journal of mathematical neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed, 49 citations in OpenAlex.
- Slow negative feedback enhances robustness of square-wave bursting.Journal of computational neuroscience · 2023Article
- Sex differences in pituitary corticotroph excitability.Frontiers in physiology · 2023Article
- Dynamics Analysis of Firing Patterns in Pre-Bötzinger Complex Neurons Model.Frontiers in computational neuroscience · 2021Article
- Article
- From global to local: exploring the relationship between parameters and behaviors in models of electrical excitability.Journal of computational neuroscience · 2016Article
- Power-Law Dynamics of Membrane Conductances Increase Spiking Diversity in a Hodgkin-Huxley Model.PLoS computational biology · 2016Article
- Large conductance Ca²⁺-activated K⁺ (BK) channels promote secretagogue-induced transition from spiking to bursting in murine anterior pituitary corticotrophs.The Journal of physiology · 2015Article
- A geometric understanding of how fast activating potassium channels promote bursting in pituitary cells.Journal of computational neuroscience · 2014Article
- The relationship between two fast/slow analysis techniques for bursting oscillations.Chaos (Woodbury, N.Y.) · 2012Article
- Dynamical systems analysis of spike-adding mechanisms in transient bursts.Journal of mathematical neuroscience · 2012Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
Abstract
Pituitary cells of the anterior pituitary gland secrete hormones in response to patterns of electrical activity. Several types of pituitary cells produce short bursts of electrical activity which are more effective than single spikes in evoking hormone release. These bursts, called pseudo-plateau bursts, are unlike bursts studied mathematically in neurons (plateau bursting) and the standard fast-slow analysis used for plateau bursting is of limited use. Using an alternative fast-slow analysis, with one fast and two slow variables, we show that pseudo-plateau bursting is a canard-induced mixed mode oscillation. Using this technique, it is possible to determine the region of parameter space where bursting occurs as well as salient properties of the burst such as the number of spikes in the burst. The information gained from this one-fast/two-slow decomposition complements the information obtained from a two-fast/one-slow decomposition.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.