Evidence map›Paper›PMID 22266883›Full record

ReviewSeminars in neurology2011

Genetics of dementia.

Henry L Paulson, Indu Igo

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in neurology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. HIV-Associated Neurocognitive Disorder (HAND): Relative Risk Factors.Current topics in behavioral neurosciences · 2021
    Article
  11. Cortical Frontoparietal Network Dysfunction inFrontiers in aging neuroscience · 2021
    Article
  12. Article
  13. Article
  14. Incidence of frontotemporal disorders in Olmsted County: A population-based study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Henry L PaulsonDepartment of Neurology, University of Michigan, Ann Arbor, Michigan 48109, USA. henryp@umich.edu
Indu Igo
University of Michigan–Ann Arbor · US

Funding

Integrating Quality Control: Studies of CHIP in Age-related NeurodegenerationR01AG034228 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PAULSON, HENRY L · 2009 to 2013
$1.5M
NIA NIH HHS R01 AG034228
6 · The paper itself

Abstract

Genetic factors are now recognized to play an important role in most age-related dementias. Although other factors, including aging itself, contribute to dementia, in this review the authors focus on the role of specific disease-causing genes and genetic factors in the most common age-related dementias. They review each dementia within the context of a genes/environment continuum, with varying levels of genetic versus environmental influence. All major classes of dementia will be discussed but greatest attention will be given to the most common dementia, Alzheimer's disease, for which several new genetic factors were recently identified.

Indexed as

Alzheimer DiseaseApolipoproteins EDementiaDNA Repeat ExpansionFrontotemporal Lobar DegenerationGenetic Predisposition to DiseaseHumansHuntington DiseaseLewy Body DiseaseMutationPrion DiseasesApolipoproteins E

Identifiers

PMID22266883
PMCPMC3545709
OpenAlexW2040142519

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.