ReviewNature reviews. Microbiology2012
Genome analyses highlight the different biological roles of cellulases.
Review in Nature reviews. Microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
78 citing papers in PubMed, 213 citations in OpenAlex.
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- Discovery and functional characterization of endoglucanases fromApplied and environmental microbiology · 2026Article
- The physiological functions of the Cbp2D and Cbp2E proteins are important for insoluble cellulose-dependent growth inApplied and environmental microbiology · 2025Article
- Understanding the Impact of Salt Stress on Plant Pathogens Through Phenotypic and Transcriptomic Analysis.Plants (Basel, Switzerland) · 2025Article
- Microbial Diversity and Biodegradation Mechanism of Microorganisms in the Dingtao M2 Tomb.International journal of molecular sciences · 2024Article
- Article
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- Biochemical Characterization of Novel GH6 Endoglucanase fromFoods (Basel, Switzerland) · 2023Article
- Effects of Different Nitrogen Levels on Lignocellulolytic Enzyme Production and Gene Expression under Straw-State Cultivation inInternational journal of molecular sciences · 2023Article
- Biocatalytic potential ofiScience · 2023Article
- Interaction Networks Are Driven by Community-Responsive Phenotypes in a Chitin-Degrading Consortium of Soil Microbes.mSystems · 2022Article
- The Structure of Stable Cellulolytic Consortia Isolated from Natural Lignocellulosic Substrates.International journal of molecular sciences · 2022Article
- Multikingdom interactions govern the microbiome in subterranean cultural heritage sites.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Comparative Genomic Analyses of the GenusMicroorganisms · 2022Article
- Deciphering Genomes: Genetic Signatures of Plant-AssociatedFrontiers in plant science · 2022Article
- Isolation of3 Biotech · 2022Article
- Characterization of a GH8 β-1,4-Glucanase fromJournal of microbiology and biotechnology · 2021Article
- Microbial Communities Influence Soil Dissolved Organic Carbon Concentration by Altering Metabolite Composition.Frontiers in microbiology · 2021Article
- Plant cell wall architecture guided design of CBM3-GH11 chimeras with enhanced xylanase activity using a tandem repeat left-handed β-3-prism scaffold.Computational and structural biotechnology journal · 2021Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Cellulolytic enzymes have been the subject of renewed interest owing to their potential role in the conversion of plant lignocellulose to sustainable biofuels. An analysis of ∼1,500 complete bacterial genomes, presented here, reveals that ∼40% of the genomes of sequenced bacteria encode at least one cellulase gene. Most of the bacteria that encode cellulases are soil and marine saprophytes, many of which encode a range of enzymes for cellulose hydrolysis and also for the breakdown of the other constituents of plant cell walls (hemicelluloses and pectins). Intriguingly, cellulases are present in organisms that are usually considered as non-saprophytic, such as Mycobacterium tuberculosis, Legionella pneumophila, Yersinia pestis and even Escherichia coli. We also discuss newly emerging roles of cellulases in such non-saprophytic organisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.