Evidence map›Paper›PMID 22266776›Full record

ArticleInternational journal of cancer2012

Self-reported history of infections and the risk of non-Hodgkin lymphoma: an InterLymph pooled analysis.

Nikolaus Becker, Michael O Falster, Claire M Vajdic, Silvia de Sanjose, Otoniel Martínez-Maza, Paige M Bracci, Mads Melbye, Karin Ekström Smedby, Eric A Engels, Jennifer Turner and 21 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Epidemiology of Marginal Zone Lymphoma.Annals of lymphoma · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Risk of lymphoma subtypes by occupational exposure in Southern Italy.Journal of occupational medicine and toxicology (London, England) · 2017
    Article
  12. Article
  13. Pericardial involvement as an initial presentation of anaplastic large cell lymphoma.Canadian family physician Medecin de famille canadien · 2014
    Article
  14. Article
  15. Investigation of epstein-barr virus as a potential cause of B-cell non-Hodgkin lymphoma in a prospective cohort.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2013
    Observational
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 20 institutions in 12 countries.

Nikolaus BeckerDivision of Cancer Epidemiology, German Cancer Research Centre, Heidelberg, Germany.
Michael O Falster
Claire M Vajdic
Silvia de Sanjose
Otoniel Martínez-Maza
Paige M Bracci
Mads Melbye
Karin Ekström Smedby
Eric A Engels
Jennifer Turner
Paolo Vineis
Adele Seniori Costantini
Elizabeth A Holly
John J Spinelli
Carlo La Vecchia
Tongzhang Zheng
Brian C-H Chiu
Maurizio Montella
Pierluigi Cocco
Marc Maynadié
Lenka Foretova
Anthony Staines
Paul Brennan
Scott Davis
Richard Severson
James R Cerhan
Elizabeth C Breen
Brenda Birmann
Wendy Cozen
Andrew E Grulich
Robert Newton
University of California, Los Angeles · USUniversity of California, San Francisco · USUNSW Sydney · AUBC Cancer Agency · CABiotherapy of Genetic Diseases, Inflammatory Disorders and Cancers · FRCentre International de Recherche sur le Cancer · FRDivision of Cancer Epidemiology and GeneticsDouglass Hanly Moir Pathology · AUDublin City University · IEGerman Cancer Research Center · DEHarvard University · USHull York Medical School · GBImperial College London · GBInstitut Català d'Oncologia · ESIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITKarolinska Institutet · SEMario Negri Institute for Pharmacological Research · ITMasaryk Memorial Cancer Institute · CZMayo Clinic · USNational Centre for Clinical Research on Emerging Drugs · AU

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Thomas James Lynch · 1985 to 2026
$296.4M
Molecular Epidemiology of non Hodgkin's LymphomaR01CA087014 · NCI · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI HOLLY, ELIZABETH A. · 2001 to 2005
$6.7M
Molecular Epidemiology of NHL and CLLR01CA092153 · NCI · MAYO CLINIC ROCHESTER · PI CERHAN, JAMES R · 2003 to 2012
$6.7M
SURVEILLANCE, EPIDEMIOLOGY, AND END RESULTS--SEERN01PC065064 · PC · WAYNE STATE UNIVERSITY · PI SCHWARTZ, ANN G · 1996 to 2000
$4.5M
SURVEILLANCE EPIDEMIOLOGY &END RESULTS PROGRAMN01PC067008 · PC · UNIVERSITY OF IOWA · PI LYNCH, CHARLES · 1996 to 2000
$3.8M
SURVEILLANCE EPIDEMIOLOGY &END RESULTS PROGRAMN01PC067009 · PC · FRED HUTCHINSON CANCER RESEARCH CENTER · PI THOMAS, DAVID B · 1996 to 2000
$3.0M
Genetic Susceptibility to Non-Hodgkins LymphomaR01CA104682 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI SKIBOLA, CHRISTINE F. · 2003 to 2012
$2.6M
SURVEILLANCE EPIDEMIOLOGY &END RESULTS PROGRAMN01PC067010 · PC · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROSS, RONALD K · 1996 to 2000
$2.4M
Energy Balance, IGF Dysregulation and Multiple MyelomaK07CA115687 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BIRMANN, BRENDA M · 2006 to 2010
$796k
DETERMINANTS OF THE SECULAR INCREASE IN NHLR01CA069269 · NCI · STATENS SERUM INSTITUT · PI MELBYE, MADS · 1998 to 2000
$644k
EPIDEMIOLOGY OF NON HODGKINS'S LYMPHOMA DATA ANALYSISR03CA089745 · NCI · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI HOLLY, ELIZABETH A. · 2001 to 2002
$148k
HAIR DYE USE AND RISK OF NONHODGKINS LYMPHOMAR01CA062006 · NCI · YALE UNIVERSITY · PI ZHENG, TONGZHANG · 1995 to 2000
$125k
CIHRNCI NIH HHS CA104682NCI NIH HHS CA69269-02NCI NIH HHS CA87014NCI NIH HHS CA89745NCI NIH HHS CA92153NCI NIH HHS K07 CA115687NCI NIH HHS N01 PC065064NCI NIH HHS N01 PC067008NCI NIH HHS N01 PC067009NCI NIH HHS N01 PC067010NCI NIH HHS P30 CA015704NCI NIH HHS PC65064NCI NIH HHS PC67008NCI NIH HHS PC67009NCI NIH HHS PC67010NCI NIH HHS PC71105NCI NIH HHS R01 CA045614NCI NIH HHS R01 CA051086NCI NIH HHS R01 CA062006NCI NIH HHS R01 CA069269NCI NIH HHS R01 CA087014NCI NIH HHS R01 CA092153NCI NIH HHS R01 CA104682NCI NIH HHS R03 CA089745
6 · The paper itself

Abstract

We performed a pooled analysis of data on self-reported history of infections in relation to the risk of non-Hodgkin lymphoma (NHL) from 17 case-control studies that included 12,585 cases and 15,416 controls aged 16-96 years at recruitment. Pooled odds ratios (OR) and 95% confidence intervals (95% CI) were estimated in two-stage random-effect or joint fixed-effect models, adjusting for age, sex and study centre. Data from the 2 years before diagnosis (or date of interview for controls) were excluded. A self-reported history of infectious mononucleosis was associated with an excess risk of NHL (OR = 1.26, 95% CI = 1.01-1.57 based on data from 16 studies); study-specific results indicate significant (I(2) = 51%, p = 0.01) heterogeneity. A self-reported history of measles or whooping cough was associated with an approximate 15% reduction in risk. History of other infection was not associated with NHL. We find little clear evidence of an association between NHL risk and infection although the limitations of data based on self-reported medical history (particularly of childhood illness reported by older people) are well recognized.

Indexed as

AdolescentAdultAgedAged, 80 and overCase-Control StudiesFemaleHumansInfectious MononucleosisLymphoma, Non-HodgkinMaleMiddle AgedRiskSelf ReportYoung Adult

Identifiers

PMID22266776
PMCPMC3406230
OpenAlexW2001175105

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.