ArticleInvestigative ophthalmology & visual science2012
Optical coherence tomography as a rapid, accurate, noncontact method of visualizing the palisades of Vogt.
Article in Investigative ophthalmology & visual science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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Who cites it
25 citing papers in PubMed, 50 citations in OpenAlex.
- Correlation of Multimodal Clinical Imaging With the Whole-Slide- and Superresolution-Based Immunohistological Structure of the Corneal Limbal Stroma.Investigative ophthalmology & visual science · 2025Article
- In Vivo Contactless, Cellular-Resolution Imaging of the Healthy and Pathological Human Limbus With 250-kHz Point-Scanning SD-OCT.Translational vision science & technology · 2024Article
- Fabrication and Characterisation of Hydrogels with Reversible Wrinkled Surfaces for Limbal Study and Reconstruction.Gels (Basel, Switzerland) · 2023Article
- Human limbal epithelial stem cell regulation, bioengineering and function.Progress in retinal and eye research · 2021Review
- Stem Cell Niche Microenvironment: Review.Bioengineering (Basel, Switzerland) · 2021Review
- Spectral-domain optical coherence tomography for evaluating palisades of Vogt in ocular surface disorders with limbal involvement.Scientific reports · 2021Observational
- Accurate tissue interface segmentation via adversarial pre-segmentation of anterior segment OCT images.Biomedical optics express · 2019Article
- Limbal stem cells: identity, developmental origin, and therapeutic potential.Wiley interdisciplinary reviews. Developmental biology · 2018Review
- The diagnosis of limbal stem cell deficiency.The ocular surface · 2018Review
- A method for quantifying limbal stem cell niches using OCT imaging.The British journal of ophthalmology · 2017Article
- Optical Coherence Tomography Imaging of the Palisades of Vogt to Assist Clinical Evaluation and Surgical Planning in a Case of Limbal Stem-Cell Deficiency.Eye & contact lens · 2017Article
- Article
- Correlation between the existence of the palisades of Vogt and limbal epithelial thickness in limbal stem cell deficiency.Clinical & experimental ophthalmology · 2017Observational
- Ultrahigh-resolution OCT imaging of the human cornea.Biomedical optics express · 2017Article
- In vivo imaging of palisades of Vogt in dry eye versus normal subjects using en-face spectral-domain optical coherence tomography.PloS one · 2017Article
- Identifying the Palisades of Vogt in Human Ex Vivo Tissue.The ocular surface · 2016Article
- Measurement of corneal and limbal epithelial thickness by anterior segment optical coherence tomography and in vivo confocal microscopy.BMC ophthalmology · 2016Article
- The Palisades of Vogt in Congenital Corneal Opacification (An American Ophthalmological Society Thesis).Transactions of the American Ophthalmological Society · 2016Article
- Using optical coherence tomography to assess the role of age and region in corneal epithelium and palisades of vogt.Medicine · 2016Article
- Functional imaging for regenerative medicine.Stem cell research & therapy · 2016Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeThis study explored the efficacy of optical coherence tomography (OCT) as a high-resolution, noncontact method for imaging the palisades of Vogt by correlating OCT and confocal microscopy images.
methodsHuman limbal rims were acquired and imaged with OCT and confocal microscopy. The area of the epithelial basement membrane in each of these sets was digitally reconstructed, and the models were compared.
resultsOCT identified the palisades within the limbus and exhibited excellent structural correlation with immunostained tissue imaged by confocal microscopy.
conclusionsOCT successfully identified the limbal palisades of Vogt that constitute the corneal epithelial stem cell niche. These findings offer the exciting potential to characterize the architecture of the palisades in vivo, to harvest stem cells for transplantation more accurately, to track palisade structure for better diagnosis, follow-up and staging of treatment, and to assess and intervene in the progression of stem cell depletion by monitoring changes in the structure of the palisades.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.