Evidence map›Paper›PMID 22266088›Full record

ArticleDrug and alcohol dependence2012

Lifetime ATS use and increased HIV risk among not-in-treatment opiate injectors in Malaysia.

Marek C Chawarski, Balasingam Vicknasingam, Mahmud Mazlan, Richard S Schottenfeld

Registry-linked trialAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05325476 (Testing of the JomPrEP App for HIV Prevention Among Malaysian MSM), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05325476 nacompletednot on this mapstarted 2023, after this paper: background citation

Testing of the JomPrEP App for HIV Prevention Among Malaysian MSM

TypeinterventionalSponsorUniversity of ConnecticutRan2023 to 2025Enrolled268ConditionsHIV Prevention ProgramArmsJomPrEP App, Inactivated JomPrEP app
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 35 citations in OpenAlex.

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  12. Substance Abuse and the HIV Situation in Malaysia.Journal of food and drug analysis · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Marek C ChawarskiYale University School of Medicine, New Haven, CT 06519, USA. marek.chawarski@yale.edu
Balasingam Vicknasingam
Mahmud Mazlan
Richard S Schottenfeld
Yale University · USUniversiti Sains Malaysia · MY

Funding

IMPROVING EFFICACY OF DRUG ABUSE TREATMENTK24DA000445 · NIDA · YALE UNIVERSITY · PI SCHOTTENFELD, RICHARD S · 2000 to 2009
$1.3M
NIDA NIH HHS K24 DA000445PHS HHS NIDA K24 DA00445
6 · The paper itself

Abstract

backgroundMalaysia has been experiencing significant drug abuse problems since the 1970s, and drug abuse is the major driver of HIV transmission in Malaysia. We investigated risk factors for HIV associated with use of amphetamine type stimulants (ATS) among not-in-treatment opiate injectors in Malaysia.

methodsBetween October of 2006 and May of 2008, we conducted a series of surveys in three major urban areas of Malaysia. A total of 732 opiate IDUs (679 males and 53 females) were enrolled in the three surveys. The survey instruments consisted of a structured interview on demographic characteristics, drug use history (including year of first use, and past month history of use of illicit drugs; lifetime and past month history of IDU or needle or equipment sharing), and HIV status.

resultsThere were 194/704 (27.6%) HIV positive participants in the sample. Two factors were significantly associated with HIV infection in this sample: lifetime history of ATS use (OR [95%CI]: 2.3 [1.5-3.6]) and lifetime history of sharing of injection equipment (OR [95% CI]: 4.2 [1.8-9.8]). Both HIV-positive and HIV-negative participants reported high levels of current needle/equipment sharing practices: 82% vs. 75%, respectively.

conclusionsATS use spread rapidly in the study sample after 1997 and is associated with an increased risk of HIV infection in this population already at high risk because of opiate IDU. Out-of-treatment IDUs in Malaysia engage in high risk behaviors regardless of their HIV status. Increased education and public health prevention measures are needed to reduce HIV transmission risks in this population.

Indexed as

Illicit DrugsRisk-TakingAdultAmphetaminesCentral Nervous System StimulantsFemaleHIV InfectionsHIV SeropositivityHumansMalaysiaMaleMiddle AgedNeedle SharingOpioid-Related DisordersRiskRisk FactorsAmphetaminesCentral Nervous System StimulantsIllicit Drugs

Identifiers

PMID22266088
PMCPMC4641448
OpenAlexW2060033845

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.