Is the safety of lithium no longer in the balance?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. [Side effects and risk profile of lithium: critical assessment of a systematic review and meta-analysis].Der Nervenarzt · 2013
   Pooled it
2. A phenotypic screen of Marfan syndrome iPSC-derived vascular smooth muscle cells uncovers GSK3β as a new target.Stem cell reports · 2023
   Article
3. Lithium orotate: A superior option for lithium therapy?Brain and behavior · 2021
   Review
4. Exploring the Effects of Greek Yogurt Supplementation and Exercise Training on Serum Lithium and Its Relationship With Musculoskeletal Outcomes in Men.Frontiers in nutrition · 2021
   Article
5. Trace Elements in Human Nutrition (II) - An Update.International journal of preventive medicine · 2020
   Review
6. A Low-Therapeutic Dose of Lithium Inhibits GSK3 and Enhances Myoblast Fusion in C2C12 Cells.Cells · 2019
   Article
7. Lithium and nephrotoxicity: a literature review of approaches to clinical management and risk stratification.BMC nephrology · 2018
   Review
8. Lithium Treatment Is Safe in Children With Intellectual Disability.Frontiers in molecular neuroscience · 2018
   Article
9. Towards a Unified Understanding of Lithium Action in Basic Biology and its Significance for Applied Biology.The Journal of membrane biology · 2017
   Review
10. Protection against Klebsiella pneumoniae using lithium chloride in an intragastric infection model.Antimicrobial agents and chemotherapy · 2015
    Article
11. Lithium Modulates Autophagy in Esophageal and Colorectal Cancer Cells and Enhances the Efficacy of Therapeutic Agents In Vitro and In Vivo.PloS one · 2015
    Article
12. Role of lithium augmentation in the management of major depressive disorder.CNS drugs · 2014
    Review
13. General medical burden in bipolar disorder: findings from the LiTMUS comparative effectiveness trial.Acta psychiatrica Scandinavica · 2014
    Article
14. Using lithium as a neuroprotective agent in patients with cancer.BMC medicine · 2012
    Review
15. Commentary on a recent review of lithium toxicity: what are its implications for clinical practice?BMC medicine · 2012
    Article

Corrections and comments

• Comment on
  Lithium toxicity profile: a systematic review and meta-analysis.2012

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as