Trial reportAmerican journal of infection control2012
Appropriate time-interval application of alcohol hand gel on reducing influenza-like illness among preschool children: a randomized, controlled trial.
Trial report in American journal of infection control, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 8 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Physical interventions to interrupt or reduce the spread of respiratory viruses.The Cochrane database of systematic reviews · 2023Pooled it
- The effect of hand hygiene frequency on reducing acute respiratory infections in the community: a meta-analysis.Epidemiology and infection · 2022Pooled it
- The effect of hand hygiene promotion programs during epidemics and pandemics of respiratory droplet-transmissible infections on health outcomes: a rapid systematic review.BMC public health · 2021Pooled it
- Physical interventions to interrupt or reduce the spread of respiratory viruses.The Cochrane database of systematic reviews · 2020Pooled it
- Rinse-free hand wash for reducing absenteeism among preschool and school children.The Cochrane database of systematic reviews · 2020Pooled it
- Effectiveness of hand hygiene interventions in reducing illness absence among children in educational settings: a systematic review and meta-analysis.Archives of disease in childhood · 2016Pooled it
- Hand hygiene and risk of influenza virus infections in the community: a systematic review and meta-analysis.Epidemiology and infection · 2014Pooled it
- Hand hygiene to reduce community transmission of influenza and acute respiratory tract infection: a systematic review.Influenza and other respiratory viruses · 2013Pooled it
- Effects of a school-based water and hygiene intervention on the health and attendance of preschool pupils in Addis Ababa, Ethiopia: a cluster-randomised controlled trial.Journal of epidemiology and community health · 2026Trial
- Assessing the Impact of a Handwashing Knowledge and Practices Program among Poor Households in Rural Bangladesh: A Cluster-Randomized Pre-Post Study.The American journal of tropical medicine and hygiene · 2023Trial
- Effectiveness of a Behavior Change Intervention with Hand Sanitizer Use and Respiratory Hygiene in Reducing Laboratory-Confirmed Influenza among Schoolchildren in Bangladesh: A Cluster Randomized Controlled Trial.The American journal of tropical medicine and hygiene · 2019Trial
- Effect of hand hygiene program among school children in Bangladesh.BMC public health · 2025Article
- Interventions promoting uptake of water, sanitation and hygiene (WASH) technologies in low- and middle-income countries: An evidence and gap map of effectiveness studies.Campbell systematic reviews · 2021Article
- Child Care in the Time of Coronavirus Disease-19: A Period of Challenge and Opportunity.The Journal of pediatrics · 2020Article
- Effect of hand hygiene intervention on the absenteeism of pre-school children in Klang Valley, Malaysia: a quasi-experimental study.World journal of pediatrics : WJP · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe studied the efficacy of different time-interval applications of alcohol hand gel as a strategy for the prevention of influenza-like illness (ILI) in preschool-age children.
methodsWe performed a classroom-based cluster randomization at a kindergarten school in Bangkok, Thailand. A total of 1437 children were placed into 3 test groups, based on the frequency of alcohol hand gel use for hand hygiene: only before lunch (q lunch), every 120 minutes (q 120), and every 60 minutes (q 60). The primary outcome was a change in the school absenteeism rate caused by ILI.
resultsThe rates of absenteeism from confirmed ILI (sick days/present days) were 0.026 in the q lunch group, 0.025 in the q 120 group, and 0.017 in the q 60 group. Significant reductions in absenteeism rates were seen when comparing the q 60 group with the q 120 group (rate difference, 0.009; 95% confidence interval [CI], -0.002 to 0.015; P = .008) and comparing the q 60 group with the q lunch group (rate difference, 0.0096; 95% CI, 0.004-0.016; P = .002). No such differences were detected between the q 120 and q lunch groups (rate difference, 0.001; 95% CI, 0.005-0.007; P = .743).
conclusionsThe compulsory hourly use of alcohol gel as classroom hand disinfection could significantly reduce the rate of absenteeism from ILI in preschool-age children.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.