ArticleCell host & microbe2012
UPEC hemolysin: more than just for making holes.
Article in Cell host & microbe, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 22 citations in OpenAlex.
- O‑Island 28 encodes a type I secretion and RTX adhesion system regulated by RstA and required for early EHEC O157:H7 adherence.Gut microbes · 2026Article
- Retrospective study on antibiotic resistance profiles of uropathogenicFrontiers in microbiology · 2026Article
- The role of uropathogenicJournal of medicine and life · 2025Review
- Retrospective Analysis of Antibiotic Resistance Patterns of UropathogenicHealth science reports · 2025Article
- Evaluation of Extended-Spectrum Beta-Lactamase Resistance in UropathogenicMicroorganisms · 2023Article
- Detection of Cyclomodulin CNF-1 Toxin-Producing Strains ofMicroorganisms · 2023Article
- Uropathogenic Escherichia coli endeavors: an insight into the characteristic features, resistance mechanism, and treatment choice.Archives of microbiology · 2023Review
- Epidemiology and characterization ofAccess microbiology · 2023Article
- Genomic Characterization of Multidrug-ResistantFrontiers in microbiology · 2020Article
- Virulence factors of uropathogenic Escherichia coli (UPEC) and correlation with antimicrobial resistance.BMC microbiology · 2019Article
- Impact of Proinflammatory Cytokines on the Virulence of UropathogenicFrontiers in microbiology · 2019Article
- Group B streptococcus exploits vaginal epithelial exfoliation for ascending infection.The Journal of clinical investigation · 2018Article
- Phenotypic Assays to Determine Virulence Factors of Uropathogenic Escherichia coli (UPEC) Isolates and their Correlation with Antibiotic Resistance Pattern.Osong public health and research perspectives · 2015Article
- sRNA-Mediated Regulation of P-Fimbriae Phase Variation in Uropathogenic Escherichia coli.PLoS pathogens · 2015Article
- Urinary tract infections: epidemiology, mechanisms of infection and treatment options.Nature reviews. Microbiology · 2015Review
- Clinical features of bacterial vaginosis in a murine model of vaginal infection with Gardnerella vaginalis.PloS one · 2013Article
Corrections and comments
- Comment on
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
During acute cystitis, uropathogenic Escherichia coli (UPEC) induce bladder epithelial cell exfoliation, which eliminates infected cells and promotes UPEC dissemination. Dhakal and Mulvey (2012) uncover the mechanism that induces this exfoliation and reintroduce the pore-forming toxin, hemolysin, as an effector that surprisingly targets multiple host pathways to facilitate infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.