Evidence map›Paper›PMID 22264426›Full record

Trial reportPrimary care diabetes2012

Impact of the Chronic Care Model on medication adherence when patients perceive cost as a barrier.

Katherine Mackey, Michael L Parchman, Luci K Leykum, Holly J Lanham, Polly H Noël, John E Zeber

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Primary care diabetes, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00482768 (Improving Risk Factors for Diabetes Complications in Primary Care), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00482768 nacompletednot on this map

Improving Risk Factors for Diabetes Complications in Primary Care

TypeinterventionalSponsorThe University of Texas Health Science Center at San AntonioRan2007 to 2013Enrolled2,493ConditionsType 2 DiabetesArmsPractice Facilitation
3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katherine MackeyDepartment of Family & Community Medicine, University of Texas Health Science Center at San Antonio, TX, United States.
Michael L Parchman
Luci K Leykum
Holly J Lanham
Polly H Noël
John E Zeber

Funding

Improving Risk Factors for Diabetes Complications in Primary CareR18DK075692 · NIDDK · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI NOEL, POLLY H · 2007 to 2011
$2.5M
NIDDK NIH HHS R18 DK075692NIDDK NIH HHS R18DK075692
6 · The paper itself

Abstract

aimsCost burdens represent a significant barrier to medication adherence among chronically ill patients, yet financial pressures may be mitigated by clinical or organizational factors, such as treatment aligned with the Chronic Care Model (CCM). This study examines how perceptions of chronic illness care attenuate the relationship between adherence and cost burden.

methodsSurveys were administered to patients at 40 small community-based primary care practices. Medication adherence was assessed using the 4-item Morisky scale, while five cost-related items documented recent pharmacy restrictions. CCM experiences were assessed via the 20-item Patient Assessment of Chronic Illness Care (PACIC). Nested random effects models determined if chronic care perceptions modified the association between medication adherence and cost-related burden.

resultsOf 1823 respondents reporting diabetes and other chronic diseases, one-quarter endorsed intrapersonal adherence barriers, while 23% restricted medication due of cost. Controlling for age and health status, the relationship between medication cost and CCM with adherence was significant; including PACIC scores attenuated cost-related problems patients with adequate or problematic adherence behavior.

conclusionsPatients experiencing treatment more consistent with the CCM reported better adherence and lower cost-related burden. Fostering highly activated patients and shared clinical decision making may help alleviate medication cost pressures and improve adherence.

Indexed as

Drug CostsHealth Knowledge, Attitudes, PracticePerceptionAdultAgedChronic DiseaseCost of IllnessCross-Sectional StudiesDelivery of Health CareFemaleFinancing, PersonalHealth Care SurveysHumansLinear ModelsLong-Term CareMale

Identifiers

PMID22264426
PMCPMC3558316

What OpenQuestion holds

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LicenceTDM
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.