Evidence map›Paper›PMID 22264110›Full record

ArticleAmerican journal on intellectual and developmental disabilities2012

Profiles of receptive and expressive language abilities in boys with comorbid fragile X syndrome and autism.

Andrea McDuffie, Sara Kover, Leonard Abbeduto, Pamela Lewis, Ted Brown

Open access · greenAbstract read
In one paragraph

Article in American journal on intellectual and developmental disabilities, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Language Development From Early Childhood to Adolescence in Youths With Fragile X Syndrome.Journal of speech, language, and hearing research : JSLHR · 2020
    Article
  10. Article
  11. Article
  12. Vocabulary comprehension in adults with fragile X syndrome (FXS).Journal of neurodevelopmental disorders · 2019
    Article
  13. Early Predictors of Later Expressive Language in Boys With Fragile X Syndrome.American journal on intellectual and developmental disabilities · 2019
    Article
  14. Article
  15. Article
  16. Noncomprehension Signaling in Males and Females With Fragile X Syndrome.Journal of speech, language, and hearing research : JSLHR · 2017
    Article
  17. Article
  18. Article
  19. Characterising repetitive behaviours in young boys with fragile X syndrome.Journal of intellectual disability research : JIDR · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Andrea McDuffieUniversity of Wisconsin-Madison, USA.
Sara Kover
Leonard Abbeduto
Pamela Lewis
Ted Brown
University of Wisconsin–Madison · USNew York State Office for People With Developmental Disabilities · US

Funding

WISCONSIN CENTER ON MENTAL RETARDATION: CORE SUPPORTP30HD003352 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI MESSING, ALBEE · 1985 to 2015
$25.2M
LINGUISTIC COMMUNICATION AND MENTAL RETARDATIONR01HD024356 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI ABBEDUTO, LEONARD J. · 1987 to 2022
$9.0M
NICHD NIH HHS P30 HD003352NICHD NIH HHS P30 HD03352NICHD NIH HHS R01 HD024356
6 · The paper itself

Abstract

Abstract The authors examined receptive and expressive language profiles for a group of verbal male children and adolescents who had fragile X syndrome along with varying degrees of autism symptoms. A categorical approach for assigning autism diagnostic classification, based on the combined use of the Autism Diagnostic Interview-Revised and the Autism Diagnostic Observation Schedule (ADOS), and a continuous approach for representing autism symptom severity, based on ADOS severity scores, were used in 2 separate sets of analyses. All analyses controlled for nonverbal IQ and chronological age. Nonverbal IQ accounted for significant variance in all language outcomes with large effect sizes. Results of the categorical analyses failed to reveal an effect of diagnostic group (fragile X syndrome-autism, fragile X syndrome-no autism) on standardized language test performance. Results of the continuous analyses revealed a negative relationship between autism symptom severity and all of the standardized language measures. Implications for representing autism symptoms in fragile X syndrome research are considered.

Indexed as

AdolescentAutistic DisorderChildCommunication DisordersComorbidityFragile X SyndromeHumansLanguage Development DisordersMaleNonverbal CommunicationSemanticsSeverity of Illness IndexVocabulary

Identifiers

PMID22264110
PMCPMC3265023
OpenAlexW2118721003

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.