Trial reportSubstance abuse2012
A randomized trial of methadone initiation prior to release from incarceration.
Trial report in Substance abuse, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 7 syntheses or guidelines pooled it, 96 citations in OpenAlex.
- Interventions to reduce harms related to drug use among people who experience incarceration: systematic review and meta-analysis.The Lancet. Public health · 2024Pooled it
- Opioid agonist treatment for people who are dependent on pharmaceutical opioids.The Cochrane database of systematic reviews · 2022Pooled it
- Interventions for female drug-using offenders.The Cochrane database of systematic reviews · 2019Pooled it
- Opioid-related treatment, interventions, and outcomes among incarcerated persons: A systematic review.PLoS medicine · 2019Pooled it
- Pharmacological interventions for drug-using offenders.The Cochrane database of systematic reviews · 2015Pooled it
- A systematic review of randomized controlled trials of interventions to improve the health of persons during imprisonment and in the year after release.American journal of public health · 2015Pooled it
- HIV prevention for adults with criminal justice involvement: a systematic review of HIV risk-reduction interventions in incarceration and community settings.American journal of public health · 2014Pooled it
- The impact of the communities that HEAL intervention on the provision of jail-based medication for opioid use disorder & linkage programs at release: Results from a randomized, wait-list controlled trial.Journal of substance use and addiction treatment · 2026Trial
- Impact of prerelease methadone on mortality among people with HIV and opioid use disorder after prison release: results from a randomized and participant choice open-label trial in Malaysia.BMC infectious diseases · 2022Trial
- Comparison of Treatment Retention of Adults With Opioid Addiction Managed With Extended-Release Buprenorphine vs Daily Sublingual Buprenorphine-Naloxone at Time of Release From Jail.JAMA network open · 2021Trial
- HIV-Risk Behavior Among Adults with Opioid Use Disorder During 12 Months Following Pre-trial Detention: Results from a Randomized Trial of Methadone Treatment.AIDS and behavior · 2021Trial
- Randomized trial of methadone treatment of arrestees: 24-month post-release outcomes.Drug and alcohol dependence · 2021Trial
- Impact of methadone treatment initiated in jail on subsequent arrest.Journal of substance abuse treatment · 2020Trial
- Initiating methadone in jail and in the community: Patient differences and implications of methadone treatment for reducing arrests.Journal of substance abuse treatment · 2019Trial
- Initiating buprenorphine treatment prior to versus after release from prison: Arrest outcomes.Drug and alcohol dependence · 2018Trial
- A randomized, open label trial of methadone continuation versus forced withdrawal in a combined US prison and jail: Findings at 12 months post-release.Drug and alcohol dependence · 2018Trial
- Do patient characteristics moderate the effect of extended-release naltrexone (XR-NTX) for opioid use disorder?Journal of substance abuse treatment · 2018Trial
- A randomized clinical trial of buprenorphine for prisoners: Findings at 12-months post-release.Drug and alcohol dependence · 2017Trial
- Methadone continuation versus forced withdrawal on incarceration in a combined US prison and jail: a randomised, open-label trial.Lancet (London, England) · 2015Trial
- HIV Prevention for People Releasing from Incarceration: A Qualitative Pre-implementation Study.Journal of general internal medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
Individuals who use heroin and illicit opioids are at high risk for infection with human immunodeficiency virus (HIV) and other blood-borne pathogens, as well as incarceration. The purpose of the randomized trial reported here is to compare outcomes between participants who initiated methadone maintenance treatment (MMT) prior to release from incarceration, with those who were referred to treatment at the time of release. Participants who initiated MMT prior to release were significantly more likely to enter treatment postrelease (P < .001) and for participants who did enter treatment, those who received MMT prerelease did so within fewer days (P = .03). They also reported less heroin use (P = .008), other opiate use (P = .09), and injection drug use (P = .06) at 6 months. Initiating MMT in the weeks prior to release from incarceration is a feasible and effective way to improve MMT access postrelease and to decrease relapse to opioid use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.