ArticleChemical science
All-optical fluorescence image recovery using modulated Stimulated Emission Depletion.
Article in Chemical science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Fluorescence-informed photoacoustic discrimination of multiple chromophores by lifetime mapping optically gated responses.Photoacoustics · 2023Article
- Out-of-Phase Imaging after Optical Modulation (OPIOM) for Multiplexed Fluorescence Imaging Under Adverse Optical Conditions.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Synchronously Amplified Photoacoustic Image Recovery (SAPhIRe).Photoacoustics · 2020Article
- Optically Activated Delayed Fluorescence.The journal of physical chemistry letters · 2017Article
- Expanding discriminative dimensions for analysis and imaging.Chemical science · 2015Article
- Optically modulated fluorescence bioimaging: visualizing obscured fluorophores in high background.Accounts of chemical research · 2014Review
- Modulated fluorophore signal recovery buried within tissue mimicking phantoms.The journal of physical chemistry. A · 2013Article
- DNA-Templated Molecular Silver Fluorophores.The journal of physical chemistry letters · 2013Article
- Different sized luminescent gold nanoparticles.Nanoscale · 2012Article
- Optical modulation and selective recovery of Cy5 fluorescence.Chemphyschem : a European journal of chemical physics and physical chemistry · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Fluorescence modulation for selective recovery of desired fluorescence signals has to date required careful fluorophore selection combined with repeated optical recovery from long-lived photoinduced dark states. Adapting an all-optical scheme, modulated Stimulated Emission Depletion generalizes such modulation schemes by eliminating the need for dark state residence by directly optically depopulating the emissive state at any externally applied frequency. Using two overlapped Gaussian laser spots with the depletion beam being intensity-modulated, fluorescence modulation is readily achieved with a depletion ratio governed by the intensity of the depleting laser. Selective image recovery of otherwise unmodulatable fluorophore signals is directly achieved through this all-optical modulation, and common STED-degrading multiphoton-excited background is readily discriminated against. Both beads and dyes in solution as well as fluorophores bound within fixed cells are readily imaged in this manner.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.