ArticleClinical & developmental immunology2012
Expression of IL-17, IL-23 and their receptors in minor salivary glands of patients with primary Sjögren's syndrome.
Article in Clinical & developmental immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 48 citations in OpenAlex.
- Investigating the potential of the Chinese herbal remedy SS-1 for the treatment of Sjögren's syndrome via the interleukin-17 signaling axis.Journal of traditional and complementary medicine · 2026Article
- Associations Between Th17 Cell Markers (IL-23R, CCR6, and IL-17) and Clinical Profiles in Sjögren's Disease.Diagnostics (Basel, Switzerland) · 2025Article
- SHED-Derived Exosomes Ameliorate Sjögren's Syndrome-Induced Hyposalivation by Suppressing Th1 Cell Response via the miR-29a-3p/T-bet Axis.ACS applied materials & interfaces · 2025Article
- Diagnosis and management of lung involvement in systemic lupus erythematosus and Sjögren's syndrome: a literature review.Therapeutic advances in musculoskeletal disease · 2021Review
- Blocking IL-17: A Promising Strategy in the Treatment of Systemic Rheumatic Diseases.International journal of molecular sciences · 2020Review
- Interleukin-17 and -22 synergy linking inflammation and EMT-dependent fibrosis in Sjögren's syndrome.Clinical and experimental immunology · 2019Article
- Salivary gland immunizationFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019Article
- Ablation of the Chaperone Protein ERdj5 Results in a Sjögren's Syndrome-Like Phenotype in Mice, Consistent With an Upregulated Unfolded Protein Response in Human Patients.Frontiers in immunology · 2019Article
- The role of RORα in salivary gland lesions in patients with primary Sjögren's syndrome.Arthritis research & therapy · 2018Article
- Inhibition of lysophosphatidic acid receptor ameliorates Sjögren's syndrome in NOD mice.Oncotarget · 2017Article
- Expression and clinical significance of IL-17 and IL-17 receptor in ulcerative colitis.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2016Article
- The genomic landscape of human immune-mediated diseases.Journal of human genetics · 2015Review
- The coexistence of Sjögren's syndrome and primary biliary cirrhosis: a comprehensive review.Clinical reviews in allergy & immunology · 2015Review
- Distribution of Peripheral Lymphocyte Populations in Primary Sjögren's Syndrome Patients.Journal of immunology research · 2015Article
- T Regulatory and T Helper 17 Cells in Primary Sjögren's Syndrome: Facts and Perspectives.Mediators of inflammation · 2015Review
- Dysregulation of the suppressor of cytokine signalling 3-signal transducer and activator of transcription-3 pathway in the aetiopathogenesis of Sjögren's syndrome.Clinical and experimental immunology · 2014Article
- T Cell-Associated Cytokines in the Pathogenesis of Sjögren's Syndrome.Journal of clinical & cellular immunology · 2013Article
- Emerging role of interleukin-22 in autoimmune diseases.Cytokine & growth factor reviews · 2013Review
- Immunoexpression of interleukin-22 and interleukin-23 in oral and cutaneous lichen planus lesions: a preliminary study.Mediators of inflammation · 2013Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The main purpose of this study was to determine the expression of interleukins-17/-23 (ILs-17/-23) and receptors of interleukins-17/-23 (IL-17R, IL-23R) in minor salivary glands (MSGs) of patients with primary Sjögren's syndrome (pSS). Expression of IL-17, IL-23 and receptors of IL-17/-23 was analyzed in MSGs from 25 patients with pSS, 25 patients with probable preclinical pSS, and 25 patients with nonautoimmune sicca syndrome by immunohistochemistry. Comparison of the expression of IL-17, IL-23 and receptors of IL-17, IL-23 in MSG of patients with pSS with probable preclinical pSS, and with nonautoimmune sicca syndrome showed significant differences between three groups. However, the expression of IL-17, IL-23 and receptors of IL-17/-23 in MSG was comparable in pSS and probable preclinical pSS patients. We did not find correlation between the expression of IL-17 and IL-23 and of IL-17R and IL-23R in patients with pSS. These results demonstrate an involvement of IL-17/-23 system in the early pSS pathogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.