Evidence map›Paper›PMID 22262436›Full record

ReviewMethods in molecular biology (Clifton, N.J.)2012

Towards a four-dimensional view of neutrophils.

Ben A Croker, Andrew W Roberts, Nicos A Nicola

Abstract readReview
In one paragraph

Review in Methods in molecular biology (Clifton, N.J.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Ben A CrokerThe Walter and Eliza Hall Institute, 1G Royal Parade, Parkville, Australia.
Andrew W Roberts
Nicos A Nicola
The Royal Melbourne Hospital · AUUniversity of Melbourne · AUWalter and Eliza Hall Institute of Medical Research · AU

Funding

Differentiation of Granulocytes and MacrophagesR37CA022556 · NCI · WALTER AND ELIZA HALL INST MEDICAL RES · PI METCALF, DONALD · 2005 to 2014
$2.3M
DIFFERENTIATION OF GRANULOCYTES AND MACROPHAGESR01CA022556 · NCI · WALTER AND ELIZA HALL INST MEDICAL RES · PI METCALF, DONALD · 1985 to 2004
$900k
NCI NIH HHS CA022556NCI NIH HHS R01 CA022556NCI NIH HHS R37 CA022556
6 · The paper itself

Abstract

Neutrophils are constitutively produced throughout adult life and are essential for host responses to many types of pathogen. Neutropenia has long been associated with poor prognosis in the clinic, yet we have an incomplete understanding of their life cycle, not only during homeostasis but also during infection and chronic inflammation. Here, we review recent advances that provide insight into the genetic and biochemical regulators of neutrophil production, function, and survival.

Indexed as

Antigen PresentationChemotaxis, LeukocyteCytokinesHumansInflammationLeukocyte ElastaseMyeloblastinNADPH OxidasesNeutropeniaNeutrophil InfiltrationNeutrophilsCytokinesLeukocyte ElastaseMyeloblastinNADPH Oxidases

Identifiers

PMID22262436
PMCPMC13359507
OpenAlexW2406409038

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.