ArticleBiophysical journal2011
Quantum dot fluorescence characterizes the nanoscale organization of T cell receptors for antigen.
Article in Biophysical journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Article
- T cell immunotherapy enhanced by designer biomaterials.Biomaterials · 2019Review
- A high fat diet containing saturated but not unsaturated fatty acids enhances T cell receptor clustering on the nanoscale.Prostaglandins, leukotrienes, and essential fatty acids · 2015Article
- Linking form to function: Biophysical aspects of artificial antigen presenting cell design.Biochimica et biophysica acta · 2015Review
- TCR Microclusters pre-exist and contain molecules necessary for TCR signal transduction.Journal of immunology (Baltimore, Md. : 1950) · 2014Article
- An induced rebinding model of antigen discrimination.Trends in immunology · 2014Review
- Magnetic field-induced T cell receptor clustering by nanoparticles enhances T cell activation and stimulates antitumor activity.ACS nano · 2014Article
- Nanoscale artificial antigen presenting cells for T cell immunotherapy.Nanomedicine : nanotechnology, biology, and medicine · 2014Article
- Selective activation of antigen-experienced T cells by anti-CD3 constrained on nanoparticles.Journal of immunology (Baltimore, Md. : 1950) · 2013Article
- Ultrabright fluorescent mesoporous silica nanoparticles for prescreening of cervical cancer.Nanomedicine : nanotechnology, biology, and medicine · 2013Article
- Modulation of MHC binding by lateral association of TCR and coreceptor.Biophysical journal · 2012Article
- Characterization of differential Toll-like receptor responses below the optical diffraction limit.Small (Weinheim an der Bergstrasse, Germany) · 2012Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Changes in the clustering of surface receptors modulate cell responses to ligands. Hence, global measures of receptor clustering can be useful for characterizing cell states. Using T cell receptor for antigen as an example, we show that k-space image correlation spectroscopy of quantum dots blinking detects T cell receptor clusters on a scale of tens of nanometers and reports changes in clustering after T cell activation. Our results offer a general approach to the global analysis of lateral organization and receptor clustering in single cells, and can thus be applied when the cell type of interest is rare.
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Registered trials
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