Evidence map›Paper›PMID 22261040›Full record

ArticleEmerging infectious diseases2012

Invasive meningococcal capsular group Y disease, England and Wales, 2007-2009.

Shamez N Ladhani, Jay Lucidarme, Lynne S Newbold, Stephen J Gray, Anthony D Carr, Jamie Findlow, Mary E Ramsay, Edward B Kaczmarski, Raymond Borrow

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 70 citations in OpenAlex.

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  14. Meningococcal pneumonia: a review.Pneumonia (Nathan Qld.) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shamez N LadhaniDepartment, Health Protection Agency Colindale, 61 Colindale Ave, London NW9 5EQ, UK. shamez.ladhani@hpa.org.uk
Jay Lucidarme
Lynne S Newbold
Stephen J Gray
Anthony D Carr
Jamie Findlow
Mary E Ramsay
Edward B Kaczmarski
Raymond Borrow

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enhanced national surveillance for invasive meningococcal disease in England and Wales identified an increase in laboratory-confirmed capsular group Y (MenY) disease from 34 cases in 2007 to 44 in 2008 and 65 in 2009. For cases diagnosed in 2009, patient median age at disease onset was 60 years; 39% of patients had underlying medical conditions, and 19% died. MenY isolates causing invasive disease during 2007-2009 belonged mainly to 1 of 4 clonal complexes (cc), cc23 (56% of isolates), cc174 (21%), cc167 (11%), and cc22 (8%). The 2009 increase resulted primarily from sequence type 1655 (cc23) (22 cases in 2009, compared with 4 cases each in 2007 and 2008). cc23 was associated with lpxL1 mutations and meningitis in younger age groups (<25 years); cc174 was associated with nonmeningitis, particularly pneumonia, in older age groups (>65 years). The increase in MenY disease requires careful epidemiologic and molecular monitoring.

Indexed as

AcyltransferasesAdolescentAdultAgedAged, 80 and overAge DistributionBacterial ProteinsChildChild, PreschoolEnglandGene Expression Regulation, BacterialHumansInfantInfant, NewbornMeningococcal InfectionsMiddle AgedAcyltransferasesBacterial ProteinsLpxL protein, bacteria

Identifiers

PMID22261040
PMCPMC3310110
OpenAlexW2171698967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.