Evidence map›Paper›PMID 22259731›Full record

ArticleInternational neurourology journal2011

Antiproliferative factor signaling and interstitial cystitis/painful bladder syndrome.

Jayoung Kim, Michael R Freeman

Abstract read
In one paragraph

Article in International neurourology journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. How many lives does CLIMP-63 have?Biochemical Society transactions · 2015
    Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jayoung KimDivision of Cancer Biology and Therapeutics, Departments of Surgery and Biomedical Sciences, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Michael R Freeman

Funding

Urethral Tissue BioengineeringP50DK065298 · NIDDK · CHILDREN'S HOSPITAL BOSTON · PI ADAM, ROSALYN M · 2003 to 2012
$9.8M
Cholesterol and Prostate HealthR01DK087806 · NIDDK · CEDARS-SINAI MEDICAL CENTER · PI FREEMAN, MICHAEL R · 2011 to 2015
$1.9M
Amoeboid Membrane Dynamics in Prostate CancerR01CA143777 · NCI · CEDARS-SINAI MEDICAL CENTER · PI FREEMAN, MICHAEL R · 2010 to 2014
$1.7M
NCI NIH HHS R01 CA143777NIDDK NIH HHS P50 DK065298NIDDK NIH HHS R01 DK087806
6 · The paper itself

Abstract

A unique glycopeptide, antiproliferative factor (APF), has been suggested as a urinary biomarker and potential mediator of long-term bladder disorder Interstitial Cystitis/Painful Bladder Syndrome. There is no known cause for this disease. Several mechanistic approaches have been employed to address the underlying mechanism whereby APF regulates cellular responses in the bladder epithelium. A summary of recent literature is provided, and is focused on signal transduction pathways and networks that are responsive to APF.

Indexed as

Human antiproliferative factor APFInterstitial CystitisSignal transduction

Identifiers

PMID22259731
PMCPMC3256302

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.