ArticleThe Korean journal of hematology2011
Evans syndrome following long-standing Hashimoto's thyroiditis and successful treatment with rituximab.
Article in The Korean journal of hematology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 12 citations in OpenAlex.
- Autoimmune Hemolytic Anemia with Autoimmune Hypothyroidism: A Case Report.JNMA; journal of the Nepal Medical Association · 2023Article
- Secondary Hemophagocytic Lymphohistiocytosis and Autoimmune Cytopenias: Case Description and Review of the Literature.Journal of clinical medicine · 2021Article
- Evans syndrome associated with sterile inflammation of the central nervous system: a case report.Journal of medical case reports · 2013Article
- Hashimoto's thyroiditis associated Evans syndrome: A rare case report on the clustered autoimmune disease triad.Indian journal of endocrinology and metabolism · 2013Article
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Authors and funding
6 authors at 1 institution in 1 country.
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Abstract
We report a case of a 51-year-old woman with Evans syndrome (autoimmune hemolytic anemia and primary immune thrombocytopenia) and hypothyroidism. She was previously diagnosed with Hashimoto's thyroiditis in 1994 (age, 35) and autoimmune hemolytic anemia (AIHA) 3 years ago. She was treated with oral prednisolone. After a period, in which the anemia waxed and waned, there was an abrupt development of thrombocytopenia (nadir 15×10(9)/L) that coincided with the tapering off of prednisolone after 3 years of administration. Because her thrombocytopenia was refractory to prednisolone, we administered rituximab (375 mg/m(2) weekly) for 4 weeks. Two weeks after the completion of the rituximab treatment, her platelet count was up to 92×10(9)/L. No intermittent peaking of thyroid stimulating hormone occurred after rituximab treatment was initiated. Evans syndrome and autoimmune thyroiditis might share common pathophysiological mechanisms. This notion supports the use of rituximab in a patient suffering from these disorders.
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