ArticleThe Korean journal of hematology2011
Splenic infarction in a patient with autoimmune hemolytic anemia and protein C deficiency.
Article in The Korean journal of hematology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Severe homozygous HbE disease: the first case report from Nepal.Oxford medical case reports · 2023Article
- Splenic Infarction Associated With Epstein-Barr Virus in an Adult With an Anatomic Anomaly: A Case Report.Cureus · 2023Article
- Multiple splenic infarctions in a dog with immune-mediated hemolytic anemia: therapeutic implications.Iranian journal of veterinary research · 2020Article
- Splenic infarct in a patient with autoimmune hemolytic anemia.Turkish journal of haematology : official journal of Turkish Society of Haematology · 2012Article
- A rare case of autoimmune hemolytic anemia with protein S deficiency with splenic infarct.Asian journal of transfusion scienceArticle
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Splenic infarction is most commonly caused by cardiovascular thromboembolism; however, splenic infarction can also occur in hematologic diseases, including sickle cell disease, hereditary spherocytosis, chronic myeloproliferative disease, leukemia, and lymphoma. Although 10% of splenic infarction is caused by hematologic diseases, it seldom accompanies autoimmune hemolytic anemia (AIHA). We report a case of a 47-year-old woman with iron deficiency anemia who presented with pain in the left upper abdominal quadrant, and was diagnosed with AIHA and splenic infarction. Protein C activity and antigen decreased to 44.0% (60-140%) and 42.0% (65-140%), respectively. Laboratory testing confirmed no clinical cause for protein C deficiency, such as disseminated intravascular coagulation, sepsis, hepatic dysfunction, or acute respiratory distress syndrome. Protein C deficiency with splenic infarction has been reported in patients with viral infection, hereditary spherocytosis, and leukemia. This is a rare case of splenic infarction and transient protein C deficiency in a patient with AIHA.
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