Evidence map›Paper›PMID 22259235›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2012

Helicobacter pylori infection and primary open-angle glaucoma: is there a connection?

Fani Tsolaki, Eleni Gogaki, Filippos Sakkias, Christina Skatharoudi, Chrysanthi Lopatatzidi, Vassilios Tsoulopoulos, Stefania Lampoura, Fotios Topouzis, Magdalini Tsolaki, Jannis Kountouras

Abstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fani TsolakiOphthalmology Department, Hippokrateion Hospital of Thessaloniki, Thessaloniki, Greece.
Eleni Gogaki
Filippos Sakkias
Christina Skatharoudi
Chrysanthi Lopatatzidi
Vassilios Tsoulopoulos
Stefania Lampoura
Fotios Topouzis
Magdalini Tsolaki
Jannis Kountouras

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glaucoma, the most common form of which is primary open-angle glaucoma (POAG), is a neurodegenerative disease which is the second most common cause of blindness worldwide. Among the factors that have been implicated in the pathophysiology of this disease is infection with Helicobacter pylori. This alleged association has caused a great deal of scientific discussion during the past decade, as the establishment of such a correlation might lead to therapeutic applications for all glaucoma patients. In this review, we assess all relevant major studies and trials in an effort to elucidate the issue.

Indexed as

apoptosisHelicobacter pyloriprimary open-angle glaucoma

Identifiers

PMID22259235
PMCPMC3259099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.