Evidence map›Paper›PMID 22259205›Full record

ArticleJournal of clinical microbiology2012

Performance assessment of a novel two-step multiple displacement amplification-PCR assay for detection of Mycobacterium tuberculosis complex in sputum specimens.

Na Wu, Yuanyuan Zhang, Jun Fu, Ruifen Zhang, Lan Feng, Yongfei Hu, Xiaoliang Li, Na Lu, Xiuqin Zhao, Yuanlong Pan and 3 more

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Na WuCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Yuanyuan Zhang
Jun Fu
Ruifen Zhang
Lan Feng
Yongfei Hu
Xiaoliang Li
Na Lu
Xiuqin Zhao
Yuanlong Pan
Jing Li
Baoli Zhu
Kanglin Wan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel two-step multiple displacement amplification-PCR (MDA-PCR) assay for tuberculosis detection in 200 sputum specimens was evaluated. The MDA-PCR assay indicated a significant increase in sensitivity and specificity compared with those of standard PCR alone.

Indexed as

Case-Control StudiesDNA, BacterialDNA Transposable ElementsHumansMolecular Diagnostic TechniquesMycobacterium tuberculosisPolymerase Chain ReactionSensitivity and SpecificitySputumTuberculosis, PulmonaryDNA, BacterialDNA Transposable Elements

Identifiers

PMID22259205
PMCPMC3318506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.