Evidence map›Paper›PMID 22259008›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2012

Stress-only imaging in patients with prior SPECT MPI: a simulation study.

John J Ryan, Rupa Mehta, Thejasvi Thiruvoipati, R Parker Ward, Kim Allan Williams

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Are SPECT MPI measures of dyssynchrony dyssynchronous?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  3. Stress-only SPECT myocardial perfusion imaging: a review.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014
    Review
  4. Stress-only imaging: faster, cheaper, less radiation. So what's the hold up?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013
    Article
  5. Clinical value of stress-only Tc-99m SPECT imaging: importance of attenuation correction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

John J RyanSection of Cardiology, Department of Medicine, University of Chicago, Chicago, IL, USA. john.ryan@uchospitals.edu
Rupa Mehta
Thejasvi Thiruvoipati
R Parker Ward
Kim Allan Williams

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to determine if omitting the repeat resting scan in patients who had prior single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI) would have an impact on the interpretation of the stress test.

backgroundCurrent guidelines recommend stress and rest imaging for SPECT MPI studies. Stress-only imaging has also entered the guidelines as a feasible option in low-risk patients but has not been studied in high-risk patients.

methodsTwo independent readers interpreted 47 consecutive MPIs with prior images to determine if the repeat resting scan had an impact on interpretation of the stress test images. In this retrospective analysis, we compared interpretation of stress-only SPECT images using the old rest image for comparison versus conventional rest-stress SPECT imaging. Both readers were blinded to study results. The primary end point of this study was a comparison of summed difference scores (SDS) from stress-only interpretation compared to standard rest-stress interpretation.

resultsIn this study, 36% (98/272) of patients had previous SPECT MPI. Of these patients, 48% (n = 47) were eligible for stress-only imaging. There was strong agreement between the SDS from the new stress versus old rest image compared with the new stress versus new rest image (r = 0.866, P < .001) with a mean difference in SDS of 0.6 ± 1.7. In this population, 41 of the 47 studies (87%) could have been performed with a stress-only SPECT MPI with comparison with the prior resting study. Starting with the stress-only protocol would have reduced the radiation in this population by 76%.

conclusionsVery similar data is obtained with stress-only imaging in patients who have a prior resting study. Our study suggests that the stress-only imaging may possibly be expanded to populations who have been studied previously or are at higher risk, reserving the option to add a resting study if the interpretation of the stress-only study is unclear.

Indexed as

Models, CardiovascularComputer SimulationCoronary Artery DiseaseExercise TestFemaleHumansMiddle AgedMyocardial Perfusion ImagingReproducibility of ResultsSensitivity and SpecificityTomography, Emission-Computed, Single-Photon

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.