Evidence map›Paper›PMID 22257169›Full record

ArticleJournal of the American Chemical Society2012

Copper-catalyzed enantioselective intramolecular alkene amination/intermolecular Heck-type coupling cascade.

Timothy W Liwosz, Sherry R Chemler

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 193 citations in OpenAlex.

  1. Article
  2. Copper-catalyzed generation of nitrogen-centered radicals and reactions thereof.ARKIVOC : free online journal of organic chemistry · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Stereoinversion of Unactivated Alcohols by Tethered Sulfonamides.Angewandte Chemie (International ed. in English) · 2019
    Article
  11. Article
  12. Article
  13. Nickel-Catalyzed Dearomative trans-1,2-Carboamination.Journal of the American Chemical Society · 2018
    Article
  14. Article
  15. Cu-Catalyzed Three-Component Carboamination of Alkenes.Journal of the American Chemical Society · 2018
    Article
  16. Diethylzinc-Mediated Metalloamination-Alkylation ofSynlett : accounts and rapid communications in synthetic organic chemistry · 2018
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Timothy W LiwoszDepartment of Chemistry, The State University of New York at Buffalo, Buffalo, New York 14260, USA.
Sherry R Chemler
University at Buffalo, State University of New York · US

Funding

New Methods for Nitrogen Heterocycle SynthesisR01GM078383 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CHEMLER, SHERRY R · 2006 to 2023
$5.6M
NIGMS NIH HHS R01 GM078383PHS HHS NIGMS 078383
6 · The paper itself

Abstract

Enantioselective copper-catalyzed cyclization of γ-alkenylsulfonamides and a δ-alkenylsulfonamide in the presence of a range of vinyl arenes results in variously functionalized 2-substituted chiral nitrogen heterocycles via a formal alkene C-H functionalization process. Application of this reaction to the concise synthesis of a 5-HT(7) receptor antagonist is demonstrated.

Indexed as

AlkenesAminationCopperCyclizationMolecular StructureOrganometallic CompoundsStereoisomerismSulfonamidesAlkenesCopperOrganometallic CompoundsSulfonamides

Identifiers

PMID22257169
PMCPMC3314298
OpenAlexW1983455719

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.