Evidence map›Paper›PMID 22254205›Full record

ArticleAmerican journal of cardiovascular disease2011

Cardioproteomics: advancing the discovery of signaling mechanisms involved in cardiovascular diseases.

Ziyou Cui, Shannamar Dewey, Aldrin V Gomes

Open access · greenAbstract read
In one paragraph

Article in American journal of cardiovascular disease, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

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  7. Phenolic Content Analysis ofPreventive nutrition and food science · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ziyou Cui
Shannamar Dewey
Aldrin V Gomes

Funding

The Role of the Proteasome in Troponin related CardiomyopathiesR01HL096819 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GOMES, ALDRIN V. · 2010 to 2014
$1.9M
NHLBI NIH HHS R01 HL096819
6 · The paper itself

Abstract

Cardioproteomics (Cardiovascular proteomics) is fast becoming an indispensible technique in deciphering changes in signaling pathways that occur in cardiovascular diseases (CVDs). The quality and availability of the instruments and bioinformatics software used for cardioproteomics continues to improve, and these techniques are now available to most cardiovascular researchers either directly or indirectly via university core centers. The heart and aorta are specialized tissues which present unique challenges to investigate. Currently, the diverse range of proteomic techniques available for cardiovascular research makes the choice of the best method or best combination of methods for the disease parameter(s) being investigated as important as the equipment used. This review focuses on proteomic techniques and their applications which have advanced our understanding of the signaling mechanisms involved in CVDs at the levels of protein complex/protein-protein interaction, post-translational modifications and signaling induced protein changes.

Indexed as

Cardioproteomicscardiovascular diseasesdrug signalingheartmass spectrometryproteomicssignaling pathway

Identifiers

PMID22254205
PMCPMC3253522
OpenAlexW104587937

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.