ReviewNutrients2010
Nonclassical vitamin D action.
Review in Nutrients, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02617771 (Impact of Vitamin D Supplementation on Recurrent Respiratory Infections in Paediatric), which is not on this map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Vitamin D Supplementation on Recurrent Respiratory Infections in Paediatric
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 125 citations in OpenAlex.
- Pooled it
- Vitamin D deficiency in critically ill children: a systematic review and meta-analysis.Critical care (London, England) · 2017Pooled it
- Vitamin D supplementation, body weight and human serum 25-hydroxyvitamin D response: a systematic review.European journal of nutrition · 2014Pooled it
- Effect of Exercise Training on 1,25(OH)Sports healthTrial
- The serum vitamin D status in adults with diabetic retinopathy: A systematic review and meta-analysis.Journal of medical biochemistry · 2026Article
- Interindividual Genetic Differences Drive Discordance Between Serum Calcidiol and Calcitriol Concentrations in Females.Endocrinology · 2025Article
- Vitamin D in the Prevention and Treatment of Inflammatory Skin Diseases.International journal of molecular sciences · 2025Review
- The Importance of Edible Medicinal Mushrooms and Their Potential Use as Therapeutic Agents Against Insulin Resistance.International journal of molecular sciences · 2025Review
- Impact of home confinement due to the COVID-19 outbreak on vitamin D levels and trends among children with pneumonia aged 1-35 months.Pediatric discovery · 2024Article
- Association of vitamin D deficiency and insufficiency with uncontrolled type 1 diabetes Mellitus among Saudi pediatric patients; a hospital-based retrospective study.Frontiers in pediatrics · 2024Article
- 25OHVitamin D Levels in a Canarian Pediatric Population with and without Type 1 Diabetes: The Role of Acidosis.Nutrients · 2023Article
- Circulating microRNAs as potential biomarkers of early vascular damage in vitamin D deficiency, obese, and diabetic patients.PloS one · 2023Article
- Cosmeceutical Therapy: Engaging the Repercussions of UVR Photoaging on the Skin's Circadian Rhythm.International journal of molecular sciences · 2022Review
- Influence of Hypovitaminosis D on the Ocurrence of Fractures.Revista brasileira de ortopedia · 2021Article
- Vitamin D Deficiency in Critically Ill Children with Sepsis: What is the Road ahead?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021Article
- Prevalence and Impact of Vitamin D Deficiency in Critically Ill Cancer Patients Admitted to the Intensive Care Unit.Nutrients · 2020Article
- Article
- Vitamin D and hematinic deficiencies in patients with recurrent aphthous stomatitis.Clinical oral investigations · 2020Article
- Serum vitamin D deficiency and risk of epithelial ovarian cancer in Lagos, Nigeria.Ecancermedicalscience · 2020Article
- The association between vitamin D status and infectious diseases of the respiratory system in infancy and childhood.Hormones (Athens, Greece) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is becoming increasingly clear that vitamin D has a broad range of actions in the human body. Besides its well-known effects on calcium/phosphate homeostasis, vitamin D influences muscle function, cardiovascular homeostasis, nervous function, and the immune response. Vitamin D deficiency/insufficiency has been associated with muscle weakness and a high incidence of various chronic diseases such as cardiovascular disease, cancer, multiple sclerosis, and type 1 and 2 diabetes. Most importantly, low vitamin D status has been found to be an independent predictor of all-cause mortality. Several recent randomized controlled trials support the assumption that vitamin D can improve muscle strength, glucose homeostasis, and cardiovascular risk markers. In addition, vitamin D may reduce cancer incidence and elevated blood pressure. Since the prevalence of vitamin D deficiency/insufficiency is high throughout the world, there is a need to improve vitamin D status in the general adult population. However, the currently recommended daily vitamin D intake of 5-15 µg is too low to achieve an adequate vitamin D status in individuals with only modest skin synthesis. Thus, there is a need to recommend a vitamin D intake that is effective for achieving adequate circulating 25-hydroxyvitamin D concentrations (>75 nmol/L).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.