ArticleNutrients2010
Continuous feedings of fortified human milk lead to nutrient losses of fat, calcium and phosphorous.
Article in Nutrients, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05484726 (Maternal Role in Sensory-motor Stimulation for Oral Feed Establishment in Preterm Neonates), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Maternal Role in Sensory-motor Stimulation for Oral Feed Establishment in Preterm Neonates: MSMS Trial
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Continuous nasogastric milk feeding versus intermittent bolus milk feeding for preterm infants less than 1500 grams.The Cochrane database of systematic reviews · 2021Pooled it
- Identification of risk factors for necrotizing enterocolitis in twins: a case-control matching analysis of over ten-years' experience.BMC pediatrics · 2024Article
- Proactive Use of a Human Milk Fat Modular in the Neonatal Intensive Care Unit: A Standardized Feeding Protocol.Nutrients · 2024Article
- Linking preterm infant gut microbiota to nasograstric enteral feeding tubes: exploring potential interactions and microbial strain transmission.Frontiers in pediatrics · 2024Article
- Human milk-derived fortifiers are linked with feed extension due to Hypoglycemia in infants <1250 g or <30 weeks: a matched retrospective chart review.Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- The Impact of Homogenization on Donor Human Milk and Human Milk-Based Fortifiers and Implications for Preterm Infant Health.Current developments in nutrition · 2022Article
- Changes in macronutrients of human milk after bolus feeding: a simulation study.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Significant Loss of Macronutrients During Passage Through Feeding Tube: An Observational Study.JPGN reports · 2020Article
- [Clinical guidelines for the diagnosis and treatment of feeding intolerance in preterm infants (2020)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Article
- Optimizing Delivery of Breast Milk for Premature Infants: Comparison of Current Enteral Feeding Systems.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2020Article
- The Fate of Fat: Pre-Exposure Fat Losses during Nasogastric Tube Feeding in Preterm Newborns.Nutrients · 2015Article
- Article
- Fortifier and cream improve fat delivery in continuous enteral infant feeding of breast milk.Nutrients · 2015Article
- Guidelines for feeding very low birth weight infants.Nutrients · 2015Review
- Calcium: a nutrient deserving a special issue.Nutrients · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Substantial losses of nutrients may occur during tube (gavage) feeding of fortified human milk. Our objective was to compare the losses of key macronutrients and minerals based on method of fortification and gavage feeding method. We used clinically available gavage feeding systems and measured pre- and post-feeding (end-point) nutrient content of calcium (Ca), phosphorus (Phos), protein, and fat. Comparisons were made between continuous, gravity bolus, and 30-minute infusion pump feeding systems, as well as human milk fortified with donor human milk-based and bovine milk-based human milk fortifier using an in vitro model. Feeding method was significantly associated with fat and Ca losses, with increased losses in continuous feeds. Fat losses in continuous feeds were substantial, with 40 ± 3 % of initial fat lost during the feeding process. After correction for feeding method, human milk fortified with donor milk-based fortifier was associated with significantly less loss of Ca (8 ± 4% vs. 28 ± 4%, p< 0.001), Phos (3 ± 4% vs. 24 ± 4%, p < 0.001), and fat (17 ± 2% vs. 25 ± 2%, p = 0.001) than human milk fortified with a bovine milk-based fortifier (Mean ± SEM).
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.