ArticleNutrients2010
Dietary phospholipids and intestinal cholesterol absorption.
Article in Nutrients, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
80 citing papers in PubMed, 1 synthesis or guideline pooled it, 234 citations in OpenAlex.
- Statins for Smith-Lemli-Opitz syndrome.The Cochrane database of systematic reviews · 2022Pooled it
- Trial
- Effectiveness of a Novel ω-3 Krill Oil Agent in Patients With Severe Hypertriglyceridemia: A Randomized Clinical Trial.JAMA network open · 2022Trial
- Changes in the lipidome in type 1 diabetes following low carbohydrate diet: Post-hoc analysis of a randomized crossover trial.Endocrinology, diabetes & metabolism · 2021Trial
- Trial
- Effects of substituting eggs for high-carbohydrate breakfast foods on the cardiometabolic risk-factor profile in adults at risk for type 2 diabetes mellitus.European journal of clinical nutrition · 2020Trial
- Trial
- Trial
- Effect of soy lecithin on fatigue and menopausal symptoms in middle-aged women: a randomized, double-blind, placebo-controlled study.Nutrition journal · 2018Trial
- Supplementation of krill oil with high phospholipid content increases sum of EPA and DHA in erythrocytes compared with low phospholipid krill oil.Lipids in health and disease · 2015Trial
- Article
- Oral lipid prodrug V2043 (1-Antimicrobial agents and chemotherapy · 2026Article
- SpiR is a gut microbial enzyme that drives cholesterol conversion.Nature communications · 2026Article
- Current management of MASLD in type 2 diabetes.Hormones (Athens, Greece) · 2026Review
- Evaluation of the Efficacy of Metformin in the Treatment of Acne Vulgaris and Its Effects on Serum Lipid Metabolism.Journal of cosmetic dermatology · 2025Article
- Serine metabolism in aging and age-related diseases.GeroScience · 2025Review
- Distribution of Dietary Phospholipids in Selected Agri-Foods: Versatile Nutraceutical Ingredients.Foods (Basel, Switzerland) · 2024Article
- Milk Fat Globule Membrane Is Associated with Lower Blood Lipid Levels in Adults: A Meta-Analysis of Randomized Controlled Trials.Foods (Basel, Switzerland) · 2024Article
- In Vivo Monitoring of Glycerolipid Metabolism in Animal Nutrition Biomodel-Fed Smart-Farm Eggs.Foods (Basel, Switzerland) · 2024Article
- Phospholipid supplementation inhibits male and female odor discrimination in mice.Frontiers in behavioral neuroscience · 2024Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Experiments carried out with cultured cells and in experimental animals have consistently shown that phospholipids (PLs) can inhibit intestinal cholesterol absorption. Limited evidence from clinical studies suggests that dietary PL supplementation has a similar effect in man. A number of biological mechanisms have been proposed in order to explain how PL in the gut lumen is able to affect cholesterol uptake by the gut mucosa. Further research is however required to establish whether the ability of PLs to inhibit cholesterol absorption is of therapeutic benefit.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.