ArticlePloS one2012
Mutation in SUMO E3 ligase, SIZ1, disrupts the mature female gametophyte in Arabidopsis.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 34 citations in OpenAlex.
- Nitrate-induced NLP1 SUMOylation regulates nitrate signaling and root nodulation.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Proteolysis in Reproduction: Lessons From Gene-Modified Organism Studies.Frontiers in endocrinology · 2022Review
- Combined Transcriptome Analysis Reveals the Ovule Abortion Regulatory Mechanisms in the Female Sterile Line ofInternational journal of molecular sciences · 2021Article
- The Maize Class-I SUMO Conjugating Enzyme ZmSCE1d Is Involved in Drought Stress Response.International journal of molecular sciences · 2019Article
- Insights into the transcriptional and post-transcriptional regulation of the rice SUMOylation machinery and into the role of two rice SUMO proteases.BMC plant biology · 2018Article
- Exploiting protein modification systems to boost crop productivity: SUMO proteases in focus.Journal of experimental botany · 2018Article
- Cell-cell communications and molecular mechanisms in plant sexual reproduction.Journal of plant research · 2018Review
- Two SUMO Proteases SUMO PROTEASE RELATED TO FERTILITY1 and 2 Are Required for Fertility in Arabidopsis.Plant physiology · 2017Article
- SUMO E3 Ligases GmSIZ1a and GmSIZ1b regulate vegetative growth in soybean .Journal of integrative plant biology · 2017Article
- A LysM Domain-Containing GeneFrontiers in plant science · 2017Article
- Salicylic Acid Regulates Pollen Tip Growth through an NPR3/NPR4-Independent Pathway.Molecular plant · 2016Article
- Arabidopsis PIAL1 and 2 promote SUMO chain formation as E4-type SUMO ligases and are involved in stress responses and sulfur metabolism.The Plant cell · 2014Article
- SUMO E3 ligase AtMMS21 is required for normal meiosis and gametophyte development in Arabidopsis.BMC plant biology · 2014Article
- Transcript profiles of maize embryo sacs and preliminary identification of genes involved in the embryo sac-pollen tube interaction.Frontiers in plant science · 2014Article
- γ-Aminobutyric acid (GABA) homeostasis regulates pollen germination and polarized growth in Picea wilsonii.Planta · 2013Article
- Emerging role of SUMOylation in plant development.Plant signaling & behavior · 2013Review
- Cold signaling and cold response in plants.International journal of molecular sciences · 2013Article
- The rice wall-associated receptor-like kinase gene OsDEES1 plays a role in female gametophyte development.Plant physiology · 2012Article
- MMS21/HPY2 and SIZ1, two Arabidopsis SUMO E3 ligases, have distinct functions in development.PloS one · 2012Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Female gametophyte is the multicellular haploid structure that can produce embryo and endosperm after fertilization, which has become an attractive model system for investigating molecular mechanisms in nuclei migration, cell specification, cell-to-cell communication and many other processes. Previous reports found that the small ubiquitin-like modifier (SUMO) E3 ligase, SIZ1, participated in many processes depending on particular target substrates and suppression of salicylic acid (SA) accumulation. Here, we report that SIZ1 mediates the reproductive process. SIZ1 showed enhanced expression in female organs, but was not detected in the anther or pollen. A defect in the siz1-2 maternal source resulted in reduced seed-set regardless of high SA concentration within the plant. Moreover, aniline blue staining and scanning electron microscopy revealed that funicular and micropylar pollen tube guidance was arrested in siz1-2 plants. Some of the embryo sacs of ovules in siz1-2 were also disrupted quickly after stage FG7. There was no significant affects of the siz1-2 mutation on expression of genes involved in female gametophyte development- or pollen tube guidance in ovaries. Together, our results suggest that SIZ1 sustains the stability and normal function of the mature female gametophyte which is necessary for pollen tube guidance.
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