ArticlePloS one2012
Perturbation dynamics of the rumen microbiota in response to exogenous butyrate.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed.
- Evaluating the Impact of High- and Low-Starch Diets on the Ruminal Microbiota of Dairy Cows.Microorganisms · 2026Article
- Effect of chemically protected sodium butyrate on growth performance, serum indicators, rumen fermentation parameters, and microbiota of Gangba sheep.Animal bioscience · 2026Article
- Effects of Adding Butyrate or Exogenous Fibrolytic Enzymes on Ruminal Epithelium, Metabolism, and Microbiota of Beef Cattle.Animals : an open access journal from MDPI · 2025Article
- Sodium Butyrate Supplementation in Whole Milk Modulates the Gastrointestinal Microbiota Without Altering the Resistome and Virulome in Preweaned Calves.Microorganisms · 2025Article
- Dynamics of Fermentation Parameters and Bacterial Community in Rumen of Calves During Dietary Protein Oscillation.Microorganisms · 2024Article
- Impact of fermented wine lees on gut microbiota and metabolic responses in Guanling crossbred cattle.BMC microbiology · 2024Article
- Integrating microbial abundance time series with fermentation dynamics of the rumen microbiome via mathematical modelling.PloS one · 2024Article
- Benefits of tributyrin on growth performance, gastrointestinal tract development, ruminal bacteria and volatile fatty acid formation of weaned Small-Tailed Han lambs.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Article
- Effects of Phlorotannins fromAnimals : an open access journal from MDPI · 2023Article
- Sodium butyrate promotes gastrointestinal development of preweaning bull calves via inhibiting inflammation, balancing nutrient metabolism, and optimizing microbial community functions.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Article
- Sodium butyrate supplementation impacts the gastrointestinal bacteria of dairy calves before weaning.Applied microbiology and biotechnology · 2023Article
- First Steps into Ruminal Microbiota Robustness.Animals : an open access journal from MDPI · 2022Review
- Effects of calcium-magnesium carbonate and calcium-magnesium hydroxide as supplemental sources of magnesium on ruminal microbiome.Translational animal science · 2022Article
- Dominant remodelling of cattle rumen microbiome byAccess microbiology · 2022Article
- The Short-Chain Fatty Acid Butyrate Attenuates Pulmonary Vascular Remodeling and Inflammation in Hypoxia-Induced Pulmonary Hypertension.International journal of molecular sciences · 2021Article
- MAP, Johne's disease and the microbiome; current knowledge and future considerations.Animal microbiome · 2021Review
- Seasonal Influence on Rumen Microbiota, Rumen Fermentation, and Enteric Methane Emissions of Holstein and Jersey Steers under the Same Total Mixed Ration.Animals : an open access journal from MDPI · 2021Article
- Taxonomy and Functional Diversity in the Fecal Microbiome of Beef Cattle Reared in Brazilian Traditional and Semi-Intensive Production Systems.Frontiers in microbiology · 2021Article
- Chemical Composition of Milk and Rumen Microbiome Diversity of Yak, Impacting by Herbage Grown at Different Phenological Periods on the Qinghai-Tibet Plateau.Animals : an open access journal from MDPI · 2020Article
- Characterization of dairy cow rumen bacterial and archaeal communities associated with grass silage and maize silage based diets.PloS one · 2020Article
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Authors and funding
5 authors.
Funding
Abstract
The capacity of the rumen microbiota to produce volatile fatty acids (VFAs) has important implications in animal well-being and production. We investigated temporal changes of the rumen microbiota in response to butyrate infusion using pyrosequencing of the 16S rRNA gene. Twenty one phyla were identified in the rumen microbiota of dairy cows. The rumen microbiota harbored 54.5±6.1 genera (mean ± SD) and 127.3±4.4 operational taxonomic units (OTUs), respectively. However, the core microbiome comprised of 26 genera and 82 OTUs. Butyrate infusion altered molar percentages of 3 major VFAs. Butyrate perturbation had a profound impact on the rumen microbial composition. A 72 h-infusion led to a significant change in the numbers of sequence reads derived from 4 phyla, including 2 most abundant phyla, Bacteroidetes and Firmicutes. As many as 19 genera and 43 OTUs were significantly impacted by butyrate infusion. Elevated butyrate levels in the rumen seemingly had a stimulating effect on butyrate-producing bacteria populations. The resilience of the rumen microbial ecosystem was evident as the abundance of the microorganisms returned to their pre-disturbed status after infusion withdrawal. Our findings provide insight into perturbation dynamics of the rumen microbial ecosystem and should guide efforts in formulating optimal uses of probiotic bacteria treating human diseases.
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