ArticleClinical, cosmetic and investigational dermatology2011
Filament formation associated with spirochetal infection: a comparative approach to Morgellons disease.
Article in Clinical, cosmetic and investigational dermatology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 34 citations in OpenAlex.
- Perceived Conjunctival Foreign Material Egress in Morgellons Disease: A Case Study.Case reports in psychiatry · 2024Article
- Treatment of Morgellons disease with doxycycline.Clinical case reports · 2021Article
- Dermatological and Genital Manifestations of Lyme Disease Including Morgellons Disease.Clinical, cosmetic and investigational dermatology · 2021Article
- Classification and Staging of Morgellons Disease: Lessons from Syphilis.Clinical, cosmetic and investigational dermatology · 2020Article
- MixedHealthcare (Basel, Switzerland) · 2019Article
- Clinical evaluation of Morgellons disease in a cohort of North American patients.Dermatology reports · 2018Article
- Persistent Borrelia Infection in Patients with Ongoing Symptoms of Lyme Disease.Healthcare (Basel, Switzerland) · 2018Article
- History of Morgellons disease: from delusion to definition.Clinical, cosmetic and investigational dermatology · 2018Review
- Detection of tick-borne infection in Morgellons disease patients by serological and molecular techniques.Clinical, cosmetic and investigational dermatology · 2018Article
- Morgellons disease: a filamentous borrelial dermatitis.International journal of general medicine · 2016Review
- Exploring the association between Morgellons disease and Lyme disease: identification of Borrelia burgdorferi in Morgellons disease patients.BMC dermatology · 2015Article
- Clinical determinants of Lyme borreliosis, babesiosis, bartonellosis, anaplasmosis, and ehrlichiosis in an Australian cohort.International journal of general medicine · 2015Article
- Relevance of chronic lyme disease to family medicine as a complex multidimensional chronic disease construct: a systematic review.International journal of family medicine · 2014Review
- Association of spirochetal infection with Morgellons disease.F1000Research · 2013Article
- Characterization and evolution of dermal filaments from patients with Morgellons disease.Clinical, cosmetic and investigational dermatology · 2013Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bovine digital dermatitis is an emerging infectious disease that causes lameness, decreased milk production, and weight loss in livestock. Proliferative stages of bovine digital dermatitis demonstrate keratin filament formation in skin above the hooves in affected animals. The multifactorial etiology of digital dermatitis is not well understood, but spirochetes and other coinfecting microorganisms have been implicated in the pathogenesis of this veterinary illness. Morgellons disease is an emerging human dermopathy characterized by the presence of filamentous fibers of undetermined composition, both in lesions and subdermally. While the etiology of Morgellons disease is unknown, there is serological and clinical evidence linking this phenomenon to Lyme borreliosis and coinfecting tick-borne agents. Although the microscopy of Morgellons filaments has been described in the medical literature, the structure and pathogenesis of these fibers is poorly understood. In contrast, most microscopy of digital dermatitis has focused on associated pathogens and histology rather than the morphology of late-stage filamentous fibers. Clinical, laboratory, and microscopic characteristics of these two diseases are compared.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.