Evidence map›Paper›PMID 22253050›Full record

ReviewGenesis (New York, N.Y. : 2000)2012

Development of Xenopus resource centers: the National Xenopus Resource and the European Xenopus Resource Center.

Esther J Pearl, Robert M Grainger, Matthew Guille, Marko E Horb

Open access · greenAbstract readReview
In one paragraph

Review in Genesis (New York, N.Y. : 2000), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Article
  3. Comparative analysis ofbioRxiv : the preprint server for biology · 2025
    Article
  4. Convergence of autism proteins at the cilium.bioRxiv : the preprint server for biology · 2025
    Article
  5. The sulfotransferase XB5850668.L is required to apportion embryonic ectodermal domains.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Article
  6. Pleiotropy of autism-associated chromatin regulators.Development (Cambridge, England) · 2023
    Article
  7. Biology · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Journal of medical genetics · 2021
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Frontiers in physiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Esther J PearlNational Xenopus Resource, Marine Biological Laboratory, Woods Hole, Massachusetts, USA.
Robert M Grainger
Matthew Guille
Marko E Horb
Marine Biological Laboratory · USUniversity of Portsmouth · GBUniversity of Virginia · US

Funding

Resource CoreP40OD010997 · OD · MARINE BIOLOGICAL LABORATORY · PI Marko E Horb · 2012 to 2026
$13.1M
National Xenopus Resource CenterP40RR025867 · NCRR · MARINE BIOLOGICAL LABORATORY · PI GRAINGER, ROBERT M · 2010 to 2011
$1.3M
Transcriptional Regulatory Networks Controlling Xenopus Pancreas DevelopmentR01DK077197 · NIDDK · MARINE BIOLOGICAL LABORATORY · PI HORB, MARKO E · 2007 to 2011
$1.1M
Biotechnology and Biological Sciences Research Council BB/F020627/1NCRR NIH HHS 5P40RR025867NCRR NIH HHS P40 RR025867NIDDK NIH HHS DK077197NIDDK NIH HHS R01 DK077197NIH HHS P40 OD010997Wellcome TrustWellcome Trust 079327Wellcome Trust 094242
6 · The paper itself

Abstract

Xenopus is an essential vertebrate model system for biomedical research that has contributed to important discoveries in many disciplines, including cell biology, molecular biology, physiology, developmental biology, and neurobiology. However, unlike other model systems no central repository/stock center for Xenopus had been established until recently. Similar to mouse, zebrafish, and fly communities, which have established stock centers, Xenopus researchers need to maintain and distribute rapidly growing numbers of inbred, mutant, and transgenic frog strains, along with DNA and protein resources, and individual laboratories struggle to accomplish this efficiently. In the last 5 years, two resource centers were founded to address this need: the European Xenopus Resource Center (EXRC) at the University of Portsmouth in England, and the National Xenopus Resource (NXR) at the Marine Biological Laboratory in Woods Hole, MA. These two centers work together to provide resources and support to the Xenopus research community. The EXRC and NXR serve as stock centers and acquire, produce, maintain and distribute mutant, inbred and transgenic Xenopus laevis and Xenopus tropicalis lines. Independently, the EXRC is a repository for Xenopus cDNAs, fosmids, and antibodies; it also provides oocytes and wild-type frogs within the United Kingdom. The NXR will complement these services by providing research training and promoting intellectual interchange through hosting mini-courses and workshops and offering space for researchers to perform short-term projects at the Marine Biological Laboratory. Together the EXRC and NXR will enable researchers to improve productivity by providing resources and expertise to all levels, from graduate students to experienced PIs. These two centers will also enable investigators that use other animal systems to take advantage of Xenopus' unique experimental features to complement their studies.

Indexed as

Animal HusbandryAnimalsBiological Specimen BanksEuropeModels, AnimalResearchUnited StatesXenopus

Identifiers

PMID22253050
PMCPMC3778656
OpenAlexW2091989272

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.