ArticleAntimicrobial agents and chemotherapy2012
Case-control study comparing de novo and daptomycin-exposed daptomycin-nonsusceptible Enterococcus infections.
Article in Antimicrobial agents and chemotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Global trends in antimicrobial resistance ofFrontiers in pharmacology · 2025Pooled it
- Daptomycin-ResistantOpen forum infectious diseases · 2022Article
- Risk Factors and Outcomes Associated With Acquisition of Daptomycin and Linezolid-Nonsusceptible Vancomycin-Resistant Enterococcus.Open forum infectious diseases · 2018Article
- Fosfomycin Enhances the Activity of Daptomycin against Vancomycin-Resistant Enterococci in an In Vitro Pharmacokinetic-Pharmacodynamic Model.Antimicrobial agents and chemotherapy · 2016Article
- Vancomycin-resistant enterococci with reduced daptomycin susceptibility in Singapore: prevalence and associated factors.Epidemiology and infection · 2016Article
- Mechanisms of drug resistance: daptomycin resistance.Annals of the New York Academy of Sciences · 2015Review
- In vitro activity of daptomycin in combination with β-lactams, gentamicin, rifampin, and tigecycline against daptomycin-nonsusceptible enterococci.Antimicrobial agents and chemotherapy · 2015Article
- The zoonotic potential of daptomycin non-susceptible enterococci.Zoonoses and public health · 2015Review
- Frequency of susceptibility testing for patients with persistent methicillin-resistant Staphylococcus aureus bacteremia.Journal of clinical microbiology · 2014Article
- Transport of daptomycin resistance genes between animals and humans as a possible mechanism for development of de novo daptomycin resistance in enterococci.Epidemiology and infection · 2013Article
- A current perspective on daptomycin for the clinical microbiologist.Clinical microbiology reviews · 2013Review
- Evolution of high-level daptomycin resistance in Enterococcus faecium during daptomycin therapy is associated with limited mutations in the bacterial genome.The Journal of antimicrobial chemotherapy · 2013Article
- Emergence of daptomycin-non-susceptible enterococci urinary tract isolates.Journal of medical microbiology · 2013Article
- Genotypic and phenotypic evaluation of the evolution of high-level daptomycin nonsusceptibility in vancomycin-resistant Enterococcus faecium.Antimicrobial agents and chemotherapy · 2012Article
- Daptomycin exposure precedes infection and/or colonization with daptomycin non-susceptible enterococcus.Antimicrobial resistance and infection control · 2012Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Understanding factors associated with de novo daptomycin-nonsusceptible Enterococcus (DNSE) infections will aid in better understanding the mechanisms of daptomycin nonsusceptibility. We conducted a case-control study to compare patients with DNSE infections who were daptomycin treatment naïve (n = 9) and those with DNSE infections who had exposure to daptomycin (n = 13). Less frequent exposure to antimicrobials, increased susceptibility to nitrofurantoin and gentamicin, and shorter duration of hospitalization were associated with de novo DNSE infection, suggesting a potential community reservoir.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.