Evidence map›Paper›PMID 22252510›Full record

ReviewPhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2012

Photoactivatable fluorophores and techniques for biological imaging applications.

Wen-hong Li, Genhua Zheng

Open access · bronzeAbstract readReview
In one paragraph

Review in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 141 citations in OpenAlex.

  1. Cilia dynamics create a dynamic barrier to penetration of the periciliary layer in human airway epithelia.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. Article
  4. Photoactivatable BODIPYs for Live-Cell PALM.Molecules (Basel, Switzerland) · 2023
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Site-Specific Incorporation of a Photoactivatable Fluorescent Amino Acid.Chembiochem : a European journal of chemical biology · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Chemical science · 2018
    Article
  19. Photochemical Barcodes.Journal of the American Chemical Society · 2018
    Article
  20. Optochemical Control of Biological Processes in Cells and Animals.Angewandte Chemie (International ed. in English) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Wen-hong LiDepartments of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA. wen-hong.li@utsouthwestern.edu
Genhua Zheng
The University of Texas Southwestern Medical Center · US

Funding

Photonic probe and techniques for biological imaging applicationsR01GM077593 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI LI, WEN-HONG · 2006 to 2015
$2.7M
NIGMS NIH HHS R01 GM077593NIGMS NIH HHS R01GM077593PHS HHS RP100456
6 · The paper itself

Abstract

Photoactivatable fluorophores (PAFs) are powerful imaging probes for tracking molecular and cellular dynamics with high spatiotemporal resolution in biological systems. Recent developments in biological microscopy have raised new demands for engineering new PAFs with improved properties, such as high two photon excitation efficiency, reversibility, cellular delivery and targeting. Here we review the history and some of the recent developments in this area, emphasizing our efforts in developing a new class of caged coumarins and related imaging methods for studying dynamic cell-cell communication through gap junction channels, and in extending the application of these caged coumarins to new areas including spatiotemporal control of microRNA activity in vivo.

Indexed as

Molecular Probe TechniquesAnimalsCell CommunicationFluorescent DyesHumansLuminescent MeasurementsPhotochemical ProcessesFluorescent Dyes

Identifiers

PMID22252510
PMCPMC3677749
OpenAlexW2141981357

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.