ReviewInternational orthopaedics2012
Microbiological diagnosis of spinal tuberculosis.
Review in International orthopaedics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- C-arm-guided percutaneous biopsy combined with mNGS: a dual-modality strategy for optimizing diagnosis and targeted management of spinal infections.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Wasting phenotype for differentiating spinal tuberculosis from spinal pyogenic infection.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Pre-extensively drug-resistant tuberculosis of the spine in a previously healthy young adult: case report.BMC infectious diseases · 2026Article
- Progress in diagnosis and treatment of primary spondylodiscitis: a systematic literature review.EFORT open reviews · 2025Article
- Tuberculosis in Turkiye: Epidemiological insights and recommendations for progress.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Review
- Clinical Features and Treatment Differences Among Tuberculous, Brucellosis, and Pyogenic Spondylitis: A Cohort Study.Infection and drug resistance · 2025Article
- Decompression and reconstruction the spinal TB lesion of a single vertebra through thoracoscopy alone or combined with foraminal endoscopy.Journal of orthopaedic surgery and research · 2024Article
- A Novel Differentiation Nomogram Model for Brucellar Spondylitis and Tuberculous Spondylitis.Infection and drug resistance · 2024Article
- Reconstruction of complicated spinal tuberculosis with long-segment fibula transplantation: a case report.BMC musculoskeletal disorders · 2023Article
- A clinical prediction model to differentiate tuberculous spondylodiscitis from pyogenic spontaneous spondylodiscitis.PloS one · 2023Article
- Neutrophil-lymphocyte ratio as a potential marker for differential diagnosis between spinal tuberculosis and pyogenic spinal infection.Journal of orthopaedic surgery and research · 2022Article
- Evaluation of the metagenomic next-generation sequencing performance in pathogenic detection in patients with spinal infection.Frontiers in cellular and infection microbiology · 2022Article
- Performances of single tube nested polymerase chain reaction and GeneXpert ultra on Formalin fixed paraffin embedded tissues in the diagnosis of tuberculous spondylodiscitis.Clinical rheumatology · 2021Article
- Retrospective Study of Bone-TB in Oman: 2002-2019.Journal of epidemiology and global health · 2021Article
- Misdiagnosed and mismanaged atypical spinal tuberculosis: A case series report.Experimental and therapeutic medicine · 2019Article
- Establishment and Initial Testing of a Medium-Sized, Surgically Feasible Animal Model for Brucellar Spondylodiscitis: A Preliminary Study.BioMed research international · 2019Article
- Diagnostic accuracy evaluation of the conventional and molecular tests for Spinal Tuberculosis in a cohort, head-to-head study.Emerging microbes & infections · 2018Article
- Could an increase in vigilance for spinal tuberculosis at primary health care level, enable earlier diagnosis at district level in a tuberculosis endemic country?African journal of primary health care & family medicine · 2018Review
- Comparison of characteristics of culture-negative pyogenic spondylitis and tuberculous spondylitis: a retrospective study.BMC infectious diseases · 2016Article
- Mycobacterium tuberculosis Contaminant Risk on Bone Marrow Aspiration Material from Iliac Bone Patients with Active Tuberculous Spondylitis.BioMed research international · 2016Observational
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to review the clinical features and diagnosis of spinal tuberculosis cases reported in the literature.
methodsA medical literature search in the Medline Pubmed database was undertaken to review tuberculosis spinal infection and extra-pulmonary tuberculosis diagnosis improvement. We introduced the following search items and boolean operators: "spinal infection", "spinal tuberculosis infection", "microbiological diagnosis of spinal tuberculosis" and "spinal tuberculosis PCR." Single cases or series without microbiological diagnosis were rejected. Manuscript language was restricted to Spanish, French, and English versions. RESULTS AND
conclusionsSpinal tuberculosis is more common in developing countries and is probably underdiagnosed. Delayed diagnosis is characteristic; it worsens the prognosis and increases morbidity. The microbiological diagnosis is crucial for several reasons. Despite surgical treatment, medical treatment with anti-tuberculous drugs is always necessary. A total of 20-40% of the spinal tuberculosis patients show another locus of infection. Pulmonary location can become a public health problem. Previously treated patients for other tuberculosis locations, incomplete treatments, or poor adherence can change the M. tuberculosis sensitivity pattern. Drug resistance test becomes a major need in the microbiology laboratory. PCR diagnostic techniques advance the diagnosis and increase the sensitivity and specificity rate.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.