SynthesisHypertension (Dallas, Tex. : 1979)2012
Significance of white-coat hypertension in older persons with isolated systolic hypertension: a meta-analysis using the International Database on Ambulatory Blood Pressure Monitoring in Relation to Cardiovascular Outcomes population.
Synthesis in Hypertension (Dallas, Tex. : 1979), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
73 citing papers in PubMed, 5 syntheses or guidelines pooled it, 182 citations in OpenAlex.
- Cardiovascular Events and Mortality in White Coat Hypertension: A Systematic Review and Meta-analysis.Annals of internal medicine · 2019Pooled it
- Prognostic Value of Masked Uncontrolled Hypertension.Hypertension (Dallas, Tex. : 1979) · 2018Pooled it
- White-coat hypertension is a risk factor for cardiovascular diseases and total mortality.Journal of hypertension · 2017Pooled it
- Blood pressure control and primary prevention of stroke: summary of the recent clinical trial data and meta-analyses.Current hypertension reports · 2013Pooled it
- Masked hypertension in diabetes mellitus: treatment implications for clinical practice.Hypertension (Dallas, Tex. : 1979) · 2013Pooled it
- Association between blood pressure categories and cardiovascular disease mortality in China.PloS one · 2021Trial
- Determinants of achieving early blood pressure control with monotherapy in a primary care setting.Journal of clinical hypertension (Greenwich, Conn.) · 2013Trial
- Effect of intensive structured care on individual blood pressure targets in primary care: multicentre randomised controlled trial.BMJ (Clinical research ed.) · 2012Trial
- Reproducibility of blood pressure dipping: relation to day-to-day variability in sleep quality.Journal of the American Society of Hypertension : JASHTrial
- Article
- Prognostic Impact of Different Definitions of White-Coat Hypertension.American journal of hypertension · 2025Article
- White Coat Hypertension & Cardiovascular Outcomes.Current hypertension reports · 2024Review
- Ambulatory Resistant Hypertension and Risk of Heart Failure in the Elderly.Diagnostics (Basel, Switzerland) · 2023Article
- Role of ambulatory blood pressure on prediction of cardiovascular disease. A cohort study.Journal of human hypertension · 2023Article
- What did we learn from the International Databases on Ambulatory and Home Blood Pressure in Relation to Cardiovascular Outcome?Hypertension research : official journal of the Japanese Society of Hypertension · 2023Review
- Prevalence and associated factors of hypertension among primary school children: A cross-sectional study in Kuching, Sarawak.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2023Article
- Home blood pressure monitoring: a position statement from the Korean Society of Hypertension Home Blood Pressure Forum.Clinical hypertension · 2022Review
- Individuals' Experiences of Being Screened for Hypertension in Dental Health Care - "No Big Deal".Patient preference and adherence · 2022Article
- Comparison of community and clinic-based blood pressure measurements: A cross-sectional study from Haiti.PLOS global public health · 2022Article
- The Key Role of Ambulatory Blood Pressure Monitoring in the Detection of Masked Hypertension and Other Phenomena in Frail Geriatric Patients.Medicina (Kaunas, Lithuania) · 2021Article
13 more citing papers are in PubMed but not listed here.
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26 authors at 1 institution in 1 country.
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Abstract
The significance of white-coat hypertension in older persons with isolated systolic hypertension remains poorly understood. We analyzed subjects from the population-based 11-country International Database on Ambulatory Blood Pressure Monitoring in Relation to Cardiovascular Outcomes database who had daytime ambulatory blood pressure (BP; ABP) and conventional BP (CBP) measurements. After excluding persons with diastolic hypertension by CBP (≥90 mm Hg) or by daytime ABP (≥85 mm Hg), a history of cardiovascular disease, and persons <18 years of age, the present analysis totaled 7295 persons, of whom 1593 had isolated systolic hypertension. During a median follow-up of 10.6 years, there was a total of 655 fatal and nonfatal cardiovascular events. The analyses were stratified by treatment status. In untreated subjects, those with white-coat hypertension (CBP ≥140/<90 mm Hg and ABP <135/<85 mm Hg) and subjects with normal BP (CBP <140/<90 mm Hg and ABP <135/<85 mm Hg) were at similar risk (adjusted hazard rate: 1.17 [95% CI: 0.87-1.57]; P=0.29). Furthermore, in treated subjects with isolated systolic hypertension, the cardiovascular risk was similar in elevated conventional and normal daytime systolic BP as compared with those with normal conventional and normal daytime BPs (adjusted hazard rate: 1.10 [95% CI: 0.79-1.53]; P=0.57). However, both treated isolated systolic hypertension subjects with white-coat hypertension (adjusted hazard rate: 2.00; [95% CI: 1.43-2.79]; P<0.0001) and treated subjects with normal BP (adjusted hazard rate: 1.98 [95% CI: 1.49-2.62]; P<0.0001) were at higher risk as compared with untreated normotensive subjects. In conclusion, subjects with sustained hypertension who have their ABP normalized on antihypertensive therapy but with residual white-coat effect by CBP measurement have an entity that we have termed, "treated normalized hypertension." Therefore, one should be cautious in applying the term "white-coat hypertension" to persons receiving antihypertensive treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.