ArticleApplied microbiology and biotechnology2012
Comparison and characterization of α-amylase inducers in Aspergillus nidulans based on nuclear localization of AmyR.
Article in Applied microbiology and biotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 38 citations in OpenAlex.
- Research Advances on the Functions of Transcriptional Regulators in Filamentous Fungi.Microorganisms · 2026Review
- Physiological ER stress caused by amylase production induces regulated Ire1-dependent mRNA decay in Aspergillus oryzae.Communications biology · 2023Article
- srdA mutations suppress the rseA/cpsA deletion mutant conidiation defect in Aspergillus nidulans.Scientific reports · 2023Article
- Profiling multi-enzyme activities of3 Biotech · 2022Article
- Article
- Induction and Repression of Hydrolase Genes inFrontiers in microbiology · 2021Review
- Development of genetic tools for the thermophilic filamentous fungusBiotechnology for biofuels · 2020Article
- Characterizing the role of Zn cluster family transcription factor ZcfA in governing development in two Aspergillus species.PloS one · 2020Article
- Conservation and diversity of the regulators of cellulolytic enzyme genes in Ascomycete fungi.Current genetics · 2017Review
- The pathway intermediate 2-keto-3-deoxy-L-galactonate mediates the induction of genes involved in D-galacturonic acid utilization in Aspergillus niger.FEBS letters · 2017Article
- Regulators of plant biomass degradation in ascomycetous fungi.Biotechnology for biofuels · 2017Review
- The amyR-deletion strain of Aspergillus niger CICC2462 is a suitable host strain to express secreted protein with a low background.Microbial cell factories · 2016Article
- Closely related fungi employ diverse enzymatic strategies to degrade plant biomass.Biotechnology for biofuels · 2015Article
- Identification of α-amylase by random and specific mutagenesis of Texcoconibacillus texcoconensis 13CCT strain isolated from extreme alkaline-saline soil of the former Lake Texcoco (Mexico).Folia microbiologica · 2014Article
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4 authors at 1 institution in 1 country.
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Abstract
AmyR, a fungal transcriptional activator responsible for induction of amylolytic genes in Aspergillus nidulans, localizes to the nucleus in response to the physiological inducer isomaltose. Maltose, kojibiose, and D: -glucose were also found to trigger the nuclear localization of GFP-AmyR. Isomaltose- and kojibiose-triggered nuclear localization was not inhibited by the glucosidase inhibitor, castanospermine, while maltose-triggered localization was inhibited. Thus, maltose itself does not appear to be an direct inducer, but its degraded or transglycosylated product does. Non-metabolizable D: -glucose analogues were also able to trigger the nuclear localization, implying that these sugars, except maltose, directly function as the inducers of AmyR nuclear entry. The inducing activity of D: -glucose was 4 orders-of-magnitude weaker compared with isomaltose. Although D: -glucose has the ability to induce α-amylase production, this activity would generally be masked by CreA-dependent carbon catabolite repression. Significant induction of α-amylase by D: -glucose was observed in creA-defective A. nidulans.
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