Trial reportJournal of child and adolescent psychopharmacology2012
Treatment of youth depression in primary care under usual practice conditions: observational findings from Youth Partners in Care.
Trial report in Journal of child and adolescent psychopharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Approaches to early intervention for common mental health problems in young people: a systematic review.BMC medicine · 2025Pooled it
- A Systematic Review of External Validity in Pediatric Integrated Primary Care Trials.Journal of pediatric psychology · 2020Pooled it
- Quality improvement, implementation, and dissemination strategies to improve mental health care for children and adolescents: a systematic review.Implementation science : IS · 2017Pooled it
- Universal mental health screening in pediatric primary care: a systematic review.Journal of the American Academy of Child and Adolescent Psychiatry · 2013Pooled it
- Improving Care Linkage for Racial-Ethnic Minority Youths Receiving Emergency Department Treatment for Suicidality: SAFETY-A.Psychiatric services (Washington, D.C.) · 2023Trial
- Integrated Primary Medical-Behavioral Health Care for Adolescent and Young Adult Depression: Predictors of Service Use in the Youth Partners in Care Trial.Journal of pediatric psychology · 2017Trial
- Longitudinal associations between depression and problematic substance use in the Youth Partners in Care study.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2013Trial
- Characterizing Measurement-Based Care in the Texas Youth Depression and Suicide Research Network (TX-YDSRN).Child psychiatry and human development · 2025Article
- Evidence-Based Youth Suicide Prevention and Intervention in Pediatric Primary Care Settings.Pediatric clinics of North America · 2024Review
- Evidence-based guidelines for anxiety, depression, obsessive-compulsive disorder and Tourette syndrome in children and youth: A rapid review.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2024Review
- CARIBOU-1: A pilot controlled trial of an Integrated Care Pathway for the treatment of depression in adolescents.JCPP advances · 2022Article
- Suicide in the pediatric population: screening, risk assessment and treatment.International review of psychiatry (Abingdon, England) · 2020Review
- The ReThink study: a 3-arm parallel randomized trial of cognitive bias modification, with and without adherence promotion, for adolescent anxiety disorder: trial design and protocol.BMC psychiatry · 2019Article
- Long-Run Trends in Antidepressant Use Among Youths After the FDA Black Box Warning.Psychiatric services (Washington, D.C.) · 2018Article
- Using the Knowledge Base of Health Services Research to Redefine Health Care Systems.Journal of general internal medicine · 2015Review
- Acculturation differences in communicating information about child mental health between Latino parents and primary care providers.Journal of immigrant and minority health · 2014Article
- Improving care for depression and suicide risk in adolescents: innovative strategies for bringing treatments to community settings.Annual review of clinical psychology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesThe effectiveness of treatments for youth depression in primary care, under usual practice conditions, is largely unstudied. This study aims at estimating the effect of "appropriate treatment," defined as treatment that approximates guideline standards, on clinical outcomes for depressed primary care youth patients by using observational analyses from a randomized trial.
methodsParticipants were 344 youths aged 13-21 enrolled in the Youth Partners in Care trial. Youths screening positive for depression from six primary care practices in five different health care organizations were randomly assigned to either (1) usual care enhanced by provider education on depression evaluation and management, or (2) a quality improvement (QI) intervention designed to improve access to antidepressant medications and/or cognitive behavior therapy for depression; usual practice conditions otherwise applied. Observational analysis was conducted on the effects of appropriate treatment (antidepressant medication use by algorithms or 6 or more psychotherapy visits) on severe depression (Center for Epidemiologic Studies-Depression score ≥ 24) at 6 months. Selection into treatment is accounted for by using instrumental variables analysis, with randomized QI intervention status as the instrument.
resultsAt 6 months, youths receiving "appropriate treatment," compared with others, were significantly less likely to have severe depression (10.9% vs. 45.2%, p<0.0001). Similar findings were observed among youths with depressive disorders and sub-syndromal depressive symptoms, and among Latino and other youths.
conclusionsAmong depressed primary care youths, care that approximates guideline standards but retains leniency substantially reduces the likelihood of severe depression at 6 months. Such findings apply to youths with or without depressive disorder, and among Latino youth.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.